鼻腔和鼻窦三维模型的鼻腔阻力数值模拟。
Numerical Simulation of Nasal Resistance Using Three-dimensional Models of the Nasal Cavity and Paranasal Sinus.
机构信息
Department of Otolaryngology, Head and Neck Surgery, Tokai University School of Medicine, 143 Shimokasuya, Isehara, Kanagawa 259-1193, Japan.
出版信息
Tokai J Exp Clin Med. 2023 Jul 20;48(2):56-61.
OBJECTIVE
Previously, we used a nasal cavity model to analyze the intranasal airflow dynamics and numerically calculate the nasal resistance value. In this study, We attempted clarify the parameters influencing nasal resistance by newly developed computer model.
METHODS
The computer simulation model was developed from the structures of nasal airway tract adopted from 1.0-mm slice computed tomography (CT) obtained from the 2 of the healthy volunteers. (model 1: the one at 35-year-old man, model 2: 25-year-old man.) We have calculated the nasal resistance by computer simulation calculations of both model 1 and model 2. These calculated values were compared with the values obtained from the established method of rhinomanometry. For the simulation, Fluent 17.2® (ANSYS, American) was employed for f luid a nalysis u sing the continuity equation for 3D incompressible flow and the Navies-Stokes equation for the basic equations. Both models were laminar models. The SIMPLE calculation method using the finite volume method was employed here, and the quadratic precision upwind difference method was used to discretize the convection terms.
RESULTS
The measured (simulation) values in Model 1 were 0.69 (0.48), 1.10 (0.41), and 0.42 (0.22) Pa/cm/s on the right, left, and both sides, whereas those in Model 2 were 0.72 (0.21), 0.32 (0.09), and 0.22 (0.06) Pa/cm/s, respectively.
CONCLUSION
Our results suggest that nasal resistance is possibly affected by the length of the inferior turbinate and the cross-sectional area of the choana and nasopharynx. Further experiments using additional nasal cavity and paranasal sinus models are warranted.
目的
我们之前使用鼻腔模型分析了鼻腔内气流动力学,并对鼻腔阻力值进行了数值计算。在本研究中,我们尝试通过新开发的计算机模型来阐明影响鼻腔阻力的参数。
方法
计算机模拟模型是根据从 2 名健康志愿者的 1.0 毫米切片计算机断层扫描(CT)获得的鼻气道结构开发的。(模型 1:35 岁男性,模型 2:25 岁男性。)我们通过对模型 1 和模型 2 进行计算机模拟计算来计算鼻腔阻力。将这些计算值与通过鼻测压法建立的方法获得的值进行了比较。对于模拟,使用 Fluent 17.2®(ANSYS,美国),使用三维不可压缩流的连续性方程和 Navies-Stokes 方程作为基本方程进行了流体分析。两个模型均为层流模型。这里采用 SIMPLE 计算方法,使用有限体积法,并采用二次精度迎风差分法离散对流项。
结果
模型 1 的右侧、左侧和双侧的测量值(模拟值)分别为 0.69(0.48)、1.10(0.41)和 0.42(0.22)Pa/cm/s,而模型 2 的测量值(模拟值)分别为 0.72(0.21)、0.32(0.09)和 0.22(0.06)Pa/cm/s。
结论
我们的结果表明,鼻腔阻力可能受到下鼻甲长度和后鼻孔及鼻咽部横截面积的影响。需要使用额外的鼻腔和副鼻窦模型进行进一步的实验。