Institute of Neuroscience and Physiology, Speech and Language Pathology Unit, Sahlgrenska Academy at the University of Gothenburg, Gothenburg, Sweden.
Centre for Teaching and Learning, Medical Faculty, Lund University, Lund, Sweden.
Clin Linguist Phon. 2024 Apr 2;38(4):359-380. doi: 10.1080/02699206.2023.2226305. Epub 2023 Jun 26.
Impaired lexical retrieval is common in persons with low-grade glioma (LGG). Several studies have reported a discrepancy between subjective word-finding difficulties and results on formal tests. Analysis of spontaneous speech might be more sensitive to signs of word-finding difficulties, hence we aimed to explore disfluencies in a spontaneous-speech task performed by participants with presumed LGG before and after surgery. Further, we wanted to explore how the presence of disfluencies in spontaneous speech differed in the participants with and without objectively established lexical-retrieval impairment and with and without self-reported subjective experience of impaired language, speech and communication. Speech samples of 26 persons with presumed low-grade glioma were analysed with regard to disfluency features. The post-operative speech samples had a higher occurrence of fillers, implying more disfluent language production. The participants performed worse on two of the word fluency tests, and after surgery the number of participants who were assessed as having an impaired lexical retrieval had increased from 6 to 12. The number of participants who experienced a change in their language, speech or communication had increased from 9 to 12. Additional comparisons showed that those with impaired lexical retrieval had a higher proportion of false starts after surgery than those with normal lexical retrieval, and differences in articulation rate and speech rate, favouring those not having experienced any change in language, speech or communication. Taken together, the findings from this study strengthen the existing claim that temporal aspects of language and speech are important when assessing persons with gliomas.
语言流畅性受损在低级别胶质瘤（LGG）患者中很常见。多项研究报告称，主观词搜索困难与正式测试结果之间存在差异。自发言语分析可能对词搜索困难的迹象更为敏感，因此我们旨在探讨术前和术后疑似 LGG 患者在自发言语任务中出现的不流畅性。此外，我们还想探讨在存在和不存在客观确定的词汇检索障碍以及存在和不存在自我报告的语言、言语和沟通受损的主观体验的参与者中，自发言语中不流畅的存在情况有何不同。对 26 名疑似低级别胶质瘤患者的言语样本进行了不流畅特征分析。术后言语样本中填充词的出现频率更高，这意味着语言产出更加不流畅。有两名参与者在两项词汇流畅性测试中的表现更差，并且在手术后，被评估为词汇检索受损的参与者人数从 6 人增加到 12 人。经历语言、言语或沟通变化的参与者人数从 9 人增加到 12 人。进一步的比较表明，与那些词汇检索正常的患者相比，术后词汇检索受损的患者有更多的启动错误，并且在发音速度和语速方面存在差异，这有利于那些没有经历任何语言、言语或沟通变化的患者。总的来说，这项研究的结果进一步证实了现有的观点，即评估胶质瘤患者时，语言和言语的时间方面很重要。
