Department of Chemistry, Osmania University, Hyderabad-500 007, India.
Department of Industrial and Engineering Chemistry, Institute of Chemical Technology, Indianoil Odisha Campus, Samantpuri, Bhubaneswar 751013, India.
Org Biomol Chem. 2023 Jul 12;21(27):5587-5591. doi: 10.1039/d3ob00658a.
An efficient and one-pot synthesis of 3,3'-bisbenzofuran derivatives has been developed. The protocol involved the use of a Pd catalyst and Cu(OAc) along with molecular oxygen as the oxidant to afford bisbenzofurans a dehydrogenative homo-coupling reaction. The reaction exhibited good functional group/heterocycle tolerance and is amenable for gram scale synthesis.
开发了一种高效、一锅法合成 3,3'-联苯并呋喃衍生物的方法。该方案涉及使用 Pd 催化剂和 Cu(OAc)，同时以分子氧作为氧化剂，以脱氢偶联反应得到双苯并呋喃。该反应对官能团/杂环具有良好的耐受性，适用于克级规模的合成。
