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[急性心血管功能不全不同发展阶段心肌中脂肪酸的代谢]

[Metabolism of fatty acids in the myocardium at various stages of development of acute cardiovascular insufficiency].

作者信息

Gutnikova A R, Ovchinnokov I V, Bakhtiiarov O R

出版信息

Kardiologiia. 1986 May;26(5):88-91.

PMID:3735926
Abstract

An experimental study in dogs, concerned with patterns of myocardial metabolism during the first and second phases of acute cardiovascular failure demonstrated a disjunction of mitochondrial oxidative phosphorylation where the supplied oxygen is consumed by processes unrelated to phosphorylation during the first phase of acute cardiovascular failure. In its second phase, the transport of oxygen and oxidation substrates to the heart is disrupted.

摘要

一项针对犬类的实验研究,关注急性心血管衰竭第一阶段和第二阶段的心肌代谢模式,结果表明,在急性心血管衰竭的第一阶段,线粒体氧化磷酸化出现脱节,即所供应的氧气被与磷酸化无关的过程消耗。在第二阶段,氧气和氧化底物向心脏的转运受到破坏。

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