Khalil Abdulkarim, Ahmad Karam G, Khalil Modar, Salloum Rabab
Faculty of Dentistry, Department of Oral and Maxillofacial Surgery.
Faculty of Medicine, Department of Otorhinolaryngology, Al Mouwasat University Hospital, Damascus, Syria.
Ann Med Surg (Lond). 2023 May 10;85(6):3086-3089. doi: 10.1097/MS9.0000000000000805. eCollection 2023 Jun.
The odontogenic myxoma is a tumor of the jaws which arises from the mesenchymal portion of the tooth germ, either the dental papilla, the follicle, or the periodontal ligament. It is a slow-growing, painless, nonmetastasizing, central tumor of the jaws, chiefly the mandible. Radiographically, the classic presentation may vary from a unilocular radiolucency to a multilocular lesion with well-defined or diffuse margins. On histological study, it is composed of triangular or stellate connective cells, anastomosed by fine extensions, and embedded in abundant mucoid material.
We present the unusual case of an odontogenic myxoma involving a 37-year-old female patient, which had acquired large dimensions and involved the right half of the mandible, including the ramus; the patient was treated with large resection surgery, with satisfying medium-term results.
Early diagnosis of such lesions is very important, as the patient avoids extensive surgical procedures that involve losing a large part of the jawbones and their subsequent impact on the patient's quality of life.
Although there is no fixed treatment plan for the management of odontogenic myxoma, treatment includes surgical management that may range from simple enucleation and curettage to surgical excision; wide surgical resection is appropriate for cases of large size to avoid recurrence.
牙源性黏液瘤是一种颌骨肿瘤，起源于牙胚的间充质部分，即牙乳头、滤泡或牙周韧带。它是一种生长缓慢、无痛、不转移的颌骨中心性肿瘤，主要发生在下颌骨。影像学上，典型表现可从单房性透光区到具有清晰或模糊边缘的多房性病变不等。组织学研究显示，它由三角形或星状结缔组织细胞组成，通过细小的突起相互吻合，并嵌入丰富的黏液样物质中。
我们报告了一例罕见的牙源性黏液瘤病例，患者为一名37岁女性，肿瘤体积巨大，累及下颌骨右半部分，包括下颌支；患者接受了大范围切除手术，中期效果令人满意。
早期诊断此类病变非常重要，因为患者可以避免进行涉及下颌骨大部分缺失的广泛手术，以及避免这些手术对患者生活质量的后续影响。
虽然牙源性黏液瘤的治疗没有固定的方案，但治疗方法包括手术治疗，范围可从简单的摘除和刮除到手术切除；对于体积较大的病例，广泛的手术切除是合适的，以避免复发。
