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[自体骨软骨镶嵌异体移植术后膝关节供区发生率的系统评价]

[Systematic evaluation of the incidence of the knee donor area after autobone cartilage mosaic xentoplasty].

作者信息

Song Wen-Jie, Liang Hao-Ran, Niu Wen-Jie, Liu Yang, Ren Zhi-Yuan, Wang Xue-Ding, Duan Wang-Ping

机构信息

Department of Orthopedics, Second Clinical Hospital of Shanxi Medical University, Taiyuan 030001, Shanxi, China; Shanxi Provincial Key Laboratory of Bone and Soft Tissue Damage Repair, Taiyuan 030001, Shanxi, China.

出版信息

Zhongguo Gu Shang. 2023 Jun 25;36(6):579-85. doi: 10.12200/j.issn.1003-0034.2023.06.015.

Abstract

OBJECTIVE

To provide an overview of the incidence of knee donor -site morbidity after autologous osteochondral mosaicplasty.

METHODS

A comprehensive search was conducted in PubMed, EMbase, Wanfang Medical Network, and CNKI databases from January 2010 to April 20, 2021. Relevant literature was selected based on predefined inclusion and exclusion criteria, and data were evaluated and extracted. The correlation between the number and size of transplanted osteochondral columns and donor-site morbidity was analyzed.

RESULTS

A total of 13 literatures were included, comprising a total of 661 patients. Statistical analysis revealed an incidence of knee donor-site morbidity at 8.6% (57/661), with knee pain being the most common complaint, accounting for 4.2%(28/661). There was no significant correlation between the number of osteochondral columns and postoperative donor-site incidence (=0.424, =10), nor between the diameter size of osteochondral columns and postoperative donor-site incidence(=0.699, =7).

CONCLUSION

Autologous osteochondral mosaicplasty is associated with a considerable incidence of knee donor-site morbidity, with knee pain being the most frequent complaint. There is no apparent correlation between donor-site incidence and the number and size of transplanted osteochondral columns. Donors should be informed about the potential risks.

摘要

目的

概述自体骨软骨镶嵌移植术后膝关节供区并发症的发生率。

方法

于2010年1月至2021年4月20日在PubMed、EMbase、万方医学网和中国知网数据库中进行全面检索。根据预先设定的纳入和排除标准选择相关文献,并对数据进行评估和提取。分析移植的骨软骨柱数量和大小与供区并发症之间的相关性。

结果

共纳入13篇文献,总计661例患者。统计分析显示膝关节供区并发症的发生率为8.6%(57/661),其中膝关节疼痛是最常见的主诉,占4.2%(28/661)。骨软骨柱的数量与术后供区发生率之间无显著相关性(=0.424,=10),骨软骨柱的直径大小与术后供区发生率之间也无显著相关性(=0.699,=7)。

结论

自体骨软骨镶嵌移植与膝关节供区并发症的发生率较高相关,膝关节疼痛是最常见的主诉。供区发生率与移植的骨软骨柱数量和大小之间无明显相关性。应告知供体潜在风险。

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