Bartha Lajos, Vajda András, Duska Zsófia, Rahmeh Husam, Hangody László
Semmelweis Medical School, Orthopedic Clinic, Budapest, Hungary.
J Orthop Sports Phys Ther. 2006 Oct;36(10):739-50. doi: 10.2519/jospt.2006.2182.
Successful management of chondral and osteochondral defects of the weight-bearing joint surfaces has always been a challenge for orthopedic surgeons and rehabilitation specialists. Autologous osteochondral mosaic transplantation technique is one of the recently evolved methods to create hyaline or hyaline-like repair tissue in the pathologic area. Clinical evaluation, various imaging techniques, arthroscopy (second look), histological examination of biopsy samples, and measurements of cartilage mechanical properties are used to evaluate the merits of outcomes and quality of the transplanted cartilage. According to our investigations, good to excellent results were achieved in more than 92% of patients treated with femoral condylar implantations, 87% of those treated with tibial resurfacing, 79% of those treated with patellar and/or trochlear mosaicplasties, and 94% of those treated with talar procedures. Long-term donor-site discrepancies, assessed with use of the Bandi Score, showed that patients had 3% morbidity after mosaicplasty. Sixty-nine of 89 patients who were followed up with a second-look arthroscopy showed congruent gliding surfaces, histological evidence of the survival of the transplanted hyaline cartilage, and fibrocartilage filling of the donor sites. In a series of 831 consecutive patients, very few complications have been observed. These included 4 deep infections and 36 painful postoperative intra-articular bleedings. On the basis of these results and those of other similar studies, autologous osteochondral mosaicplasty appears to be a promising alternative for the treatment of small- and medium-sized focal chondral and osteochondral defects of the weight-bearing surfaces of the knee and other weight-bearing synovial joints.
负重关节面软骨和骨软骨缺损的成功治疗一直是骨科医生和康复专家面临的挑战。自体骨软骨镶嵌移植技术是近年来发展起来的一种在病变区域创建透明软骨或类似透明软骨修复组织的方法。临床评估、各种成像技术、关节镜检查(二次探查)、活检样本的组织学检查以及软骨力学性能测量,用于评估移植软骨的疗效和质量。根据我们的研究,在接受股骨髁植入治疗的患者中,超过92%取得了良好至优异的结果;接受胫骨表面置换治疗的患者中,87%取得了良好至优异的结果;接受髌骨和/或滑车镶嵌成形术治疗的患者中,79%取得了良好至优异的结果;接受距骨手术治疗的患者中,94%取得了良好至优异的结果。使用班迪评分评估长期供区差异,结果显示患者在镶嵌成形术后有3%的发病率。在89例接受二次关节镜检查随访的患者中,69例显示关节面滑动一致,移植透明软骨存活的组织学证据,以及供区有纤维软骨填充。在连续831例患者的系列研究中,观察到的并发症极少。这些并发症包括4例深部感染和36例术后关节内疼痛性出血。基于这些结果以及其他类似研究的结果,自体骨软骨镶嵌成形术似乎是治疗膝关节和其他负重滑膜关节负重面中小型局灶性软骨和骨软骨缺损的一种有前景的替代方法。