利奈唑胺：治疗奴卡菌属放线菌病时氨基糖苷类药物的更安全、有效的替代品。
Linezolid: a safer and effective substitute to aminoglycoside in the treatment of actinomycetoma by Nocardia species.
机构信息
Department of Dermatology, All India Institute of Medical Sciences, Raipur, 492099, Chhattisgarh, India.
出版信息
Int J Dermatol. 2023 Sep;62(9):1160-1163. doi: 10.1111/ijd.16764. Epub 2023 Jun 27.
PMID:37366290
Abstract
Actinomycetoma is chronic, suppurative, granulomatous infection caused by bacteria and requires prolonged antibiotic therapy preferrably in combinations. Nephrotoxicity is a common side effect of aminoglycosides used in the management of actinomycetoma. We report here two cases of actinomycetoma due to Nocardia species who received linezolid as a substitute to aminoglycosides after developing nephrotoxicity.
摘要
放线菌病是一种由细菌引起的慢性化脓性肉芽肿感染，需要长期的抗生素治疗，最好是联合用药。在放线菌病的治疗中使用的氨基糖苷类药物常见的副作用是肾毒性。我们在此报告两例放线菌病，由于发生了肾毒性，患者使用利奈唑胺替代氨基糖苷类药物。
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