2 型糖尿病患者的口腔健康相关生活质量和口干症。

Oral health-related quality of life and xerostomia in type 2 diabetic patients.

机构信息

Department of Oral Medicine, Dental Research Center, Dental Research Institute, Faculty of Dentistry, Isfahan University of Medical Sciences, Iran.

Department of Restorative Dentistry, School of Dentistry, Tehran University of Medical Sciences, Iran.

出版信息

Dent Med Probl. 2023 Apr-Jun;60(2):227-231. doi: 10.17219/dmp/147754.

DOI:10.17219/dmp/147754

PMID:37366296

Abstract

BACKGROUND

Diabetes mellitus (DM) is a known risk factor for xerostomia. Oral health-related quality of life (OHRQoL) is a multi-dimensional issue reflecting several effects of the oral condition on the quality of life.

OBJECTIVES

The present study aimed to assess OHRQoL and its relationship with xerostomia severity in type 2 diabetic patients.

MATERIAL AND METHODS

A total of 200 patients participated in this cross-sectional study. The Xerostomia Inventory (XI) assessed xerostomia severity and the Oral Health Impact Profile-14 (OHIP-14) questionnaire evaluated OHRQoL. In addition, the fasting blood sugar (FBS) and glycated hemoglobin (HbA1c) tests were conducted, and the results were recorded, as well as the disease duration and denture wearing. Data analysis employed the t test and Pearson's correlation coefficient.

RESULTS

The mean XI score was 22.27 ±6.92 and the mean OHIP-14 score was 13.76 ±8.41. The mean FBS, HbA1c and disease duration values were 161.23 ±49.14 mg/dL, 7.90 ±1.12% and 11.02 ±7.78 years, respectively. The OHIP-14 score correlated significantly with the XI score, age, FBS, HbA1c, the disease duration, and denture wearing (p < 0.05).

CONCLUSIONS

There was a significant correlation between OHRQoL and xerostomia severity in patients with type 2 DM. Age, denture wearing, the disease duration, and the medical management of DM also correlated significantly with OHRQoL. Treating both the underlying disease and oral health comorbidities, such as xerostomia, seems to be essential for achieving a better OHRQoL in type 2 diabetic patients.

摘要

背景

糖尿病是口干症的已知危险因素。口腔健康相关生活质量（OHRQoL）是一个多维问题，反映了口腔状况对生活质量的多种影响。

目的

本研究旨在评估 2 型糖尿病患者的 OHRQoL 及其与口干严重程度的关系。

材料与方法

共有 200 名患者参与了这项横断面研究。使用 Xerostomia Inventory（XI）评估口干严重程度，使用 Oral Health Impact Profile-14（OHIP-14）问卷评估 OHRQoL。此外，还进行了空腹血糖（FBS）和糖化血红蛋白（HbA1c）检测，并记录了检测结果、疾病持续时间和义齿佩戴情况。数据分析采用 t 检验和 Pearson 相关系数。

结果

XI 评分的平均值为 22.27 ±6.92，OHIP-14 评分的平均值为 13.76 ±8.41。FBS、HbA1c 和疾病持续时间的平均值分别为 161.23 ±49.14 mg/dL、7.90 ±1.12%和 11.02 ±7.78 年。OHIP-14 评分与 XI 评分、年龄、FBS、HbA1c、疾病持续时间和义齿佩戴情况显著相关（p<0.05）。