School of Human Kinetics, University of Ottawa, Ottawa, ON K1N 6N5, Canada.
Cancer Therapeutic Program, Ottawa Hospital Research Institute, The Ottawa Hospital, Ottawa, ON K1H 8L6, Canada.
Curr Oncol. 2023 Jun 9;30(6):5593-5614. doi: 10.3390/curroncol30060422.
Cancer-related cognitive impairment (CRCI; e.g., disrupted memory, executive functioning, and information processing) affects many young adults, causing significant distress, reducing quality of life (QoL), and thwarting their ability to engage in professional, recreational, and social experiences. The purpose of this exploratory qualitative study was to investigate young adults' lived experiences with CRCI, and any strategies (including physical activity) they use to self-manage this burdensome side effect. Sixteen young adults (M = 30.8 ± 6.0 years; 87.5% female; M = 3.2 ± 3) who reported clinically meaningful CRCI whilst completing an online survey were interviewed virtually. Four themes comprising 13 sub-themes were identified through an inductive thematic analysis: (1) , (2) , (3) , and (4) . Findings suggest CRCI is detrimental to young adults' QoL and must be addressed more systematically in practice. Results also illuminate the promise of PA in coping with CRCI, but research is needed to confirm this association, test how and why this may occur, and determine optimal PA prescriptions for young adults to self-manage their CRCI.
癌症相关认知障碍(CRCI;例如,记忆、执行功能和信息处理受损)影响许多年轻人,导致他们感到非常痛苦,降低生活质量(QoL),并阻碍他们参与专业、娱乐和社交活动的能力。本探索性定性研究旨在调查年轻人与 CRCI 的生活体验,以及他们用于自我管理这种令人痛苦的副作用的任何策略(包括体育活动)。16 名年轻人(M = 30.8 ± 6.0 岁;87.5%女性;M = 3.2 ± 3)在完成在线调查时报告了临床上有意义的 CRCI,他们通过虚拟方式接受了采访。通过归纳主题分析确定了四个主题,包括 13 个子主题:(1) ;(2) ;(3) ;(4) 。研究结果表明,CRCI 对年轻人的生活质量有害,在实践中必须更系统地加以解决。研究结果还阐明了 PA 在应对 CRCI 中的作用,但需要开展研究来证实这种关联,检验其发生的方式和原因,以及确定针对年轻人自我管理 CRCI 的最佳 PA 方案。