Interferon induction in mice by uniform salt forms of Shigella sonnei lipopolysaccharide and its components.

Interferon-inducing capacity of uniform salts of Shigella sonnei lipopolysaccharide (LPS), its polysaccharide component and lipid A were compared. Low-molecular-weight triethylamine and ethanolamine salt forms of the lipopolysaccharide were most active in interferon production. It was confirmed that lipid part of LPS is responsible for interferon-inducing activity.