Digiesi V, Cerchiai G, Mannini L, Masi F, Nassi F
Minerva Med. 1986 Jul 31;77(30-31):1407-11.
This research was carried out to define the effects on man during head-out water immersion in a bath at 38.41 +/- 0.04 degrees C (mean +/- S.E.) with a method similar to that used for therapeutical rehabilitation and time of immersion of 30 minutes. Hemorheological, hematic and hemodynamic parameters were analysed. Seventeen healthy subjects (fourteen males and three females), between the ages of 21-65 years and mean age of 29.8 +/- 2.6 years were studied. Head-out water immersion resulted in: 1) decrease in blood viscosity, red blood cells count, C-Hct and M-Hct, without significant changes in leukocytes and platelets count, MCV, plasma viscosity, erythrocyte filtration time and RCDI; 2) an increase in heart rate and a decrease in systolic and diastolic blood pressure. Thirty minutes after the end of immersion, heart rate, diastolic blood pressure and blood viscosity, measured at 0.512 sec-1 shear rate, returned to pre-immersion values; systolic blood pressure showed a slight increase but was still significantly below the basal levels; erythrocytes count, C-Hct, M-Cct and blood viscosity, measured at 94.5 sec-1 shear rate, significantly exceeded pre-immersion values. The probable pathogenesis of these observations is suggested. A matter of great interest is the study of the same parameters in elderly subjects, with or without cardiovascular diseases, or in patients using drugs affecting blood pressure, blood viscosity or hemocoagulation process.
本研究旨在通过一种类似于治疗康复的方法，在38.41±0.04摄氏度（均值±标准误）的浴池中进行30分钟的头露出水面的水浸实验，以确定其对人体的影响。分析了血液流变学、血液和血流动力学参数。研究对象为17名年龄在21 - 65岁之间、平均年龄为29.8±2.6岁的健康受试者（14名男性和3名女性）。头露出水面的水浸实验导致：1）血液粘度、红细胞计数、C - 血细胞比容和M - 血细胞比容降低，白细胞和血小板计数、平均红细胞体积、血浆粘度、红细胞过滤时间和红细胞变形指数无显著变化；2）心率增加，收缩压和舒张压降低。浸泡结束30分钟后，在0.512秒-1剪切速率下测量的心率、舒张压和血液粘度恢复到浸泡前的值；收缩压略有升高，但仍显著低于基础水平；在94.5秒-1剪切速率下测量的红细胞计数、C - 血细胞比容、M - 血细胞比容和血液粘度显著超过浸泡前的值。文中提出了这些观察结果可能的发病机制。一个非常有趣的问题是研究老年受试者（无论有无心血管疾病）或使用影响血压、血液粘度或血液凝固过程药物的患者的相同参数。
