Janda J, Zábrodský V, Spatenka J, Tůma S
Padiatr Padol. 1986;21(2):177-82.
The authors report on a boy with typical course of recent nephrotic syndrome, who developed massive thrombosis involving the iliac inferior holden veins during the standard therapy with corticosteroid. The first sign of this complication was pulmonary embolism. Thrombosis was treated by surgery, during which 3 large thrombi from veins were removed. The patient developed recurrent thrombosis occurring at the previous sites in the later stage and he died 23 days after the first sign of thromboembolic complication. Autopsy showed only minimal glomerular changes. The cause of the death was massive pulmonary embolisation. The aethiopathogenesis of the complication and preventive approach in children with nephrotic syndrome are discussed.
作者报告了一名患有近期典型肾病综合征病程的男孩，该男孩在接受皮质类固醇标准治疗期间发生了累及双侧髂总静脉的大量血栓形成。这种并发症的首个迹象是肺栓塞。血栓形成通过手术治疗，术中从静脉中取出了3个大血栓。患者在后期于先前部位出现复发性血栓形成，并在血栓栓塞并发症出现首个迹象后23天死亡。尸检仅显示肾小球有轻微变化。死亡原因是大量肺栓塞。文中讨论了该并发症的发病机制及肾病综合征患儿的预防方法。
