Bebi Carolina, Bilato Marco, Minoli Dario Guido, De Marco Erika Adalgisa, Gnech Michele, Paraboschi Irene, Boeri Luca, Fulgheri Irene, Brambilla Roberto, Campoleoni Mauro, Albo Giancarlo, Montanari Emanuele, Manzoni Gianantonio, Berrettini Alfredo
Department of Paediatric Urology, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, 20122 Milan, Italy.
Department of Urology, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, 20122 Milan, Italy.
J Clin Med. 2023 Jan 18;12(3):755. doi: 10.3390/jcm12030755.
Antegrade sclerotherapy (Tauber) effectively treats varicocele. However, fluoroscopy exposes young males to ionizing radiation. We aimed to evaluate radiation exposure and surgical outcomes after the Tauber procedure.
We retrospectively analysed data from 251 patients. Dose area product (DAP) and fluoroscopy time were recorded. The effective dose was calculated with the PCXMC software. Descriptive statistics and linear regression tested the association between clinical predictors and radiation exposure.
Median (IQR) age and body mass index (BMI) were 14 (13-16) years and 20.1 (17.9-21.6) kg/m². Five (2.1%) patients developed clinical recurrence and two (0.81%) developed complications. Median fluoroscopy time and DAP were 38.5 (27.7-54.0) s and 89.6 (62.5-143.9) cGycm. The effective dose was 0.19 (0.14-0.31) mSv. Fluoroscopy time was higher in patients with collateral veins (41 (26-49) s vs. 36 (31-61) s, = 0.02). The median amount of sclerosing agent (SA) used was 3 (3-4) ml. DAP was higher when SA > 3 mL was used (101.4 (65-183) cGycm vs. 80.5 (59-119) cGy*cm; < 0.01). At univariable linear regression, age, BMI, operative time and SA > 3 mL were associated with higher DAP (all < 0.01). At multivariable linear regression, only BMI (beta 12.9, < 0.001) and operative time (beta 1.9, < 0.01) emerged as predictors of higher DAP, after accounting for age and SA > 3 mL.
The Tauber procedure is safe and associated with low effective doses. Operative time and the patient's BMI independently predict a higher radiation dose.
顺行硬化疗法(陶伯法)可有效治疗精索静脉曲张。然而,荧光镜检查会使年轻男性暴露于电离辐射中。我们旨在评估陶伯手术后的辐射暴露情况和手术效果。
我们回顾性分析了251例患者的数据。记录剂量面积乘积(DAP)和荧光镜检查时间。使用PCXMC软件计算有效剂量。描述性统计和线性回归分析了临床预测因素与辐射暴露之间的关联。
年龄中位数(四分位间距)和体重指数(BMI)分别为14(13 - 16)岁和20.1(17.9 - 21.6)kg/m²。5例(2.1%)患者出现临床复发,2例(0.81%)出现并发症。荧光镜检查时间中位数和DAP分别为38.5(27.7 - 54.0)秒和89.6(62.5 - 143.9)cGycm。有效剂量为0.19(0.14 - 0.31)mSv。有侧支静脉的患者荧光镜检查时间更长(41(26 - 49)秒对36(31 - 61)秒,P = 0.02)。硬化剂(SA)使用量中位数为3(3 - 4)ml。当使用SA > 3 mL时DAP更高(101.4(65 - 183)cGycm对80.5(59 - 119)cGy*cm;P < 0.01)。在单变量线性回归中,年龄、BMI、手术时间和SA > 3 mL与更高的DAP相关(均P < 0.01)。在多变量线性回归中,在考虑年龄和SA > 3 mL后,只有BMI(β 12.9,P < 0.001)和手术时间(β 1.9,P < 0.01)是更高DAP的预测因素。
陶伯手术安全且有效剂量低。手术时间和患者BMI独立预测更高的辐射剂量。