Department of Internal Medicine, Hyogo Prefectural Tamba Medical Center, Tamba 669-3495, Hyogo, Japan.
Division of Community Medicine and Career Development, Kobe University Graduate School of Medicine, Kobe 650-0017, Hyogo, Japan.
Medicina (Kaunas). 2023 Jun 20;59(6):1176. doi: 10.3390/medicina59061176.
: Renal infarction is an extremely rare disease. Although more than 95% of cases are symptomatic, there have been no previously reported asymptomatic cases, without any abnormal blood and urine test findings. Furthermore, the efficacy of long-term treatment of idiopathic renal infarction remains unknown. A 63-year-old Japanese male underwent laparoscopy; a very low anterior resection of the rectum for lower rectal cancer (stage II) four years and five months prior to diagnosis with renal infarction. During the follow-up imaging studies, asymptomatic idiopathic renal infarction was found incidentally. The blood and urine test findings were normal. Contrast-enhanced computed tomography revealed a linearly bordered area of poor contrast in the dorsal region of the right kidney; however, no renal artery lesions, thromboembolic disease, or coagulation abnormalities were observed. Initial treatment with rivaroxaban 15 mg/day resulted in the remission of the infarcted lesion. The anticoagulation therapy was terminated after about 18 months without any incidences of re-infarction or bleeding events. We reported a very rare case of asymptomatic idiopathic renal infarction where blood and urine tests revealed no abnormal findings, and it was diagnosed incidentally during a post-treatment follow-up examination for lower rectal cancer. Long-term anticoagulant therapy for idiopathic renal infarction should be terminated at an appropriate time, taking the risk of bleeding into account.
肾梗死是一种极为罕见的疾病。尽管超过 95%的病例有症状,但此前没有报告过无症状病例,且血液和尿液检查均无异常。此外,特发性肾梗死的长期治疗效果尚不清楚。
一名 63 岁的日本男性在诊断为肾梗死前 4 年零 5 个月,因低位直肠癌(II 期)接受了腹腔镜下直肠低位前切除术。在随访影像学检查中,意外发现无症状特发性肾梗死。血液和尿液检查均正常。增强 CT 显示右肾背侧线性边界的低对比区域;但未观察到肾动脉病变、血栓栓塞性疾病或凝血异常。初始使用利伐沙班 15mg/天治疗后,梗死灶缓解。在没有再梗死或出血事件的情况下,大约 18 个月后停止抗凝治疗。
我们报告了一例非常罕见的无症状特发性肾梗死病例,血液和尿液检查无异常发现,是在低位直肠癌治疗后随访检查中意外诊断出来的。特发性肾梗死的长期抗凝治疗应在适当的时候终止,需考虑出血风险。