Rudlong Autumn M, Moreno Reyes Elizabet, Goddard Julie M
Department of Food Science, Cornell University, Ithaca, NY 14853, USA.
Materials (Basel). 2023 Jun 17;16(12):4446. doi: 10.3390/ma16124446.
Food borne illness remains a major threat to public health despite new governmental guidelines and industry standards. Cross-contamination of both pathogenic and spoilage bacteria from the manufacturing environment can promote consumer illness and food spoilage. While there is guidance in cleaning and sanitation procedures, manufacturing facilities can develop bacterial harborage sites in hard-to-reach areas. New technologies to eliminate these harborage sites include chemically modified coatings that can improve surface characteristics or incorporate embedded antibacterial compounds. In this article we synthesize a 16 carbon length quaternary ammonium bromide (C16QAB) modified polyurethane and perfluoropolyether (PFPE) copolymer coating with low surface energy and bactericidal properties. The introduction of PFPE to the polyurethane coatings lowered the critical surface tension from 18.07 mN m in unmodified polyurethane to 13.14 mN m in modified polyurethane. C16QAB + PFPE polyurethane was bactericidal against (>6 log reduction) and (>3 log reduction) after just eight hours of contact. The combination of low surface tension from the perfluoropolyether and antimicrobial from the quaternary ammonium bromide produced a multifunctional polyurethane coating suitable for coating on non-food contact food production surfaces to prevent survival and persistence of pathogenic and spoilage organisms.
尽管有新的政府指导方针和行业标准，但食源性疾病仍然是对公众健康的重大威胁。来自制造环境的致病细菌和腐败细菌的交叉污染会导致消费者患病和食品变质。虽然在清洁和卫生程序方面有指导，但制造设施可能会在难以触及的区域形成细菌滋生地。消除这些滋生地的新技术包括化学改性涂层，这种涂层可以改善表面特性或含有嵌入式抗菌化合物。在本文中，我们合成了一种具有低表面能和杀菌性能的16碳长度的溴化季铵盐（C16QAB）改性聚氨酯和全氟聚醚（PFPE）共聚物涂层。将PFPE引入聚氨酯涂层后，临界表面张力从未改性聚氨酯的18.07 mN/m降低到改性聚氨酯的13.14 mN/m。C16QAB + PFPE聚氨酯在接触仅八小时后就对（>6个对数减少）和（>3个对数减少）具有杀菌作用。全氟聚醚的低表面张力和季铵盐的抗菌性能相结合，产生了一种多功能聚氨酯涂层，适用于涂覆在非食品接触的食品生产表面，以防止致病和腐败微生物的存活和持续存在。
