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妊娠期糖尿病后与异常葡萄糖耐量相关的饮食模式:MyNutritype 研究。

Dietary Patterns Associated with Abnormal Glucose Tolerance following Gestational Diabetes Mellitus: The MyNutritype Study.

机构信息

Department of Dietetics, Faculty of Medicine and Health Sciences, Universiti Putra Malaysia, Serdang 43400, Selangor, Malaysia.

Diabetes Research Unit, Faculty of Medicine and Health Sciences, Universiti Putra Malaysia, Serdang 43400, Selangor, Malaysia.

出版信息

Nutrients. 2023 Jun 20;15(12):2819. doi: 10.3390/nu15122819.

DOI:10.3390/nu15122819
PMID:37375723
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10302866/
Abstract

Abnormal glucose tolerance (AGT), which includes type 2 diabetes and pre-diabetes, is highly prevalent in women post gestational diabetes mellitus (post-GDM). Dietary patterns have been associated with the risk of developing AGT in women post-GDM, but evidence in Asian populations is sparse. This study aimed to determine the association between a posteriori dietary patterns and AGT in women post-GDM. This cross-sectional study recruited 157 women post-GDM (mean age 34.8 years) from Seri Kembangan Health Clinic and Universiti Putra Malaysia. AGT was diagnosed according to the Malaysian Clinical Practice Guidelines using a 75 g 2 h oral glucose tolerance test or HbA1c. Food intake was assessed using the 2014 Malaysian Adult Nutrition Survey food frequency questionnaire. Five dietary patterns were derived using principal component analysis: 'Unhealthy', 'Fish-eggs-fruits-vegetables', 'Cereals-confectionaries', 'Legumes-dairy', and 'Meat-sugar-sweetened-beverages'. After adjusting for sociodemographic characteristics and total energy intake, the 'Cereals-confectionaries' dietary pattern was significantly associated with AGT (adjusted odds ratio 1.536, = 0.049). Targeted lifestyle modification, including dietary intervention, for women post-GDM is warranted to reduce their risk of AGT and its complications.

摘要

异常葡萄糖耐量(AGT),包括 2 型糖尿病和糖尿病前期,在患有妊娠糖尿病(post-GDM)的女性中非常普遍。饮食模式与 post-GDM 女性发生 AGT 的风险有关,但亚洲人群的证据很少。本研究旨在确定 post-GDM 女性的后天饮食模式与 AGT 之间的关联。这是一项横断面研究,在雪兰莪州塞里班让健康诊所和马来西亚博特拉大学招募了 157 名患有 post-GDM 的女性(平均年龄 34.8 岁)。根据马来西亚临床实践指南,使用 75 g 2 h 口服葡萄糖耐量试验或 HbA1c 诊断 AGT。通过 2014 年马来西亚成人营养调查食物频率问卷评估食物摄入量。使用主成分分析得出了五种饮食模式:“不健康”、“鱼-蛋-果-蔬”、“谷物-糖果”、“豆类-乳制品”和“肉-糖-甜饮料”。在调整社会人口特征和总能量摄入后,“谷物-糖果”饮食模式与 AGT 显著相关(调整后的优势比 1.536, = 0.049)。需要针对 post-GDM 女性进行有针对性的生活方式改变,包括饮食干预,以降低她们发生 AGT 及其并发症的风险。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3c25/10302866/091c2160dd3f/nutrients-15-02819-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3c25/10302866/97ca1c9a1e5d/nutrients-15-02819-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3c25/10302866/091c2160dd3f/nutrients-15-02819-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3c25/10302866/97ca1c9a1e5d/nutrients-15-02819-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3c25/10302866/091c2160dd3f/nutrients-15-02819-g002.jpg

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Dietary Patterns, Metabolomic Profile, and Nutritype Signatures Associated with Type 2 Diabetes in Women with Postgestational Diabetes Mellitus: MyNutritype Study Protocol.产后糖尿病女性中与2型糖尿病相关的饮食模式、代谢组学特征和营养型特征:MyNutritype研究方案
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