采用脱细胞异体神经移植重建技术治疗神经瘤
Neuroma Treatment With the Acellular Nerve Allograft Reconstruction Technique.
作者信息
Bell Jennifer A, Trotter Collean, Gittings Daniel, Schur Mathew, Mohty Kurt M, Lefebvre Rachel, Stevanovic Milan
机构信息
Department of Orthopaedic Surgery, University of Southern California, Los Angeles, USA.
Department of Orthopaedic Surgery, University of Southern California Keck School of Medicine, Los Angeles, USA.
出版信息
Cureus. 2023 May 27;15(5):e39567. doi: 10.7759/cureus.39567. eCollection 2023 May.
Treatment of a painful neuroma is a challenging problem for both the patient and the providers. Current surgical treatment options typically include excision of the neuroma and stump relation. However, with both treatment options, patients have high rates of persistent pain and rates of neuroma recurrence. We describe two patients with neuromas treated with our acellular nerve allograft reconstruction technique. This technique involves the excision of the neuroma and bridging the proximal nerve end to the surrounding tissue with an acellular nerve allograft. Both patients had immediate resolution of their neuropathic pain that was maintained at their final follow-up. Acellular nerve allograft reconstruction is a promising treatment option for the treatment of painful neuromas.
对于患者和医疗服务提供者而言，疼痛性神经瘤的治疗都是一个具有挑战性的问题。目前的手术治疗选择通常包括神经瘤切除和残端处理。然而，这两种治疗方法都存在患者持续性疼痛发生率高和神经瘤复发率高的问题。我们描述了两名采用脱细胞神经同种异体移植重建技术治疗神经瘤的患者。该技术包括切除神经瘤，并用脱细胞神经同种异体移植将近端神经断端与周围组织连接起来。两名患者的神经性疼痛均立即得到缓解，并在最后一次随访时仍保持缓解状态。脱细胞神经同种异体移植重建是治疗疼痛性神经瘤的一种有前景的治疗选择。
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