Pitta Gros Barbara, Roux Olivier, Eeckhout Eric, Kirsch Matthias
Department of Cardiology, Lausanne University Hospital, Lausanne, Switzerland.
University of Lausanne, Lausanne, Switzerland.
Front Cardiovasc Med. 2023 Jun 12;10:1132063. doi: 10.3389/fcvm.2023.1132063. eCollection 2023.
Paravalvular leak is one of the most common complications and is among the most important prognostic factors of short- and long-term mortality after transcatheter aortic valve implantation (TAVI). Percutaneous valvular leak repair constitutes a first-line treatment for paravalvular leaks and is associated with high success rates and few serious complications nowadays. To the best of our knowledge, this is the first case where placement of the device through the stenting of the bioprosthesis resulted in creating a new symptomatic stenosis that required surgery.
We present a case of a patient with low-flow, low-gradient aortic stenosis treated with transfemoral implantation of a biological aortic prosthesis. One month after the procedure, the patient presented with acute pulmonary oedema and a paravalvular leak was discovered, which was corrected by percutaneous repair with a plug device. Five weeks after the valvular leak repair, the patient was readmitted for heart failure. At this time, a new aortic stenosis and paravalvular leak were diagnosed and the patient was referred for surgery. The new aortic mixed diseased was caused by the positioning of the plug device through the valve's metal stenting, which resulted in a paravalvular leak and pressed against the valve's leaflets, causing valvular stenosis. The patient was referred for surgical replacement and evolved well afterward.
This case illustrates a rare complication of a complex procedure, and it highlights the need for multidisciplinary decisions and good cooperation between the cardiology and cardiac surgery teams to develop better criteria in the selection of the appropriate technique for managing paravalvular leaks after TAVI.
瓣周漏是经导管主动脉瓣植入术(TAVI)后最常见的并发症之一,也是短期和长期死亡率的最重要预后因素之一。经皮瓣膜漏修补术是瓣周漏的一线治疗方法,目前成功率高且严重并发症少。据我们所知,这是首例通过生物瓣膜支架置入装置导致出现新的有症状狭窄并需要手术治疗的病例。
我们报告一例经股动脉植入生物主动脉瓣膜治疗的低流量、低梯度主动脉狭窄患者。术后1个月,患者出现急性肺水肿,发现瓣周漏,通过封堵器经皮修复得以纠正。瓣膜漏修复术后5周,患者因心力衰竭再次入院。此时,诊断出新发主动脉狭窄和瓣周漏,患者被转诊接受手术治疗。新的主动脉混合病变是由于封堵器通过瓣膜金属支架定位,导致瓣周漏并压迫瓣膜小叶,引起瓣膜狭窄。患者被转诊接受手术置换,术后恢复良好。
本病例说明了一种复杂手术罕见的并发症,强调了多学科决策以及心脏病学和心脏外科团队之间良好合作的必要性,以便制定更好的标准来选择TAVI术后瓣周漏的合适处理技术。