Qiao Zhu, Zou Yue, Liu Shuangyan, Zhao Hu, Li Xiaodong
Department of Stomatology II, Baoding No. 1 Central Hospital of Hebei Medical University, Baoding, Hebei 071000, P.R. China.
Central Sterile Supply Department, Baoding No. 1 Central Hospital of Hebei Medical University, Baoding, Hebei 071000, P.R. China.
Exp Ther Med. 2023 May 25;26(1):344. doi: 10.3892/etm.2023.12043. eCollection 2023 Jul.
Antibody-associated vasculitis (AAV) is a systemic autoimmune disease, with hormones and immunosuppressants as its main treatment measures. However, during the treatment process, various infections such as lung infections and urinary tract infections are prone to occur, and patients with OMSI are relatively rare. The present case report describes the case of a young woman who received long-term oral glucocorticoids and immunosuppressive agents for the treatment of antineutrophil cytoplasmic (AAV). At hospital admission, the patient with a high fever and painful swelling of the left side of the mouth. The patient was diagnosed with an oral and maxillofacial space infection (OMSI). Therefore, the local incision, drainage and irrigation of abscesses were subsequently performed. Additionally, the immunosuppressive agents were discontinued, the glucocorticoid dose was reduced and intravenous antibiotic therapy was provided. The patient was discharged 1 week later in good condition. Notably, the incidence of AAV is extremely low. Although OMSI is not uncommon, the simultaneous occurrence of AAV in combination with OMSI has not been reported previously. To the best of our knowledge, this is the first reported case of AAV combined with OMSI.
抗体相关性血管炎（AAV）是一种全身性自身免疫性疾病，主要治疗措施为激素和免疫抑制剂。然而，在治疗过程中，容易发生各种感染，如肺部感染和尿路感染，而同时患有口腔颌面部间隙感染（OMSI）的患者相对少见。本病例报告描述了一名年轻女性的病例，该患者因抗中性粒细胞胞浆抗体相关性血管炎（AAV）接受长期口服糖皮质激素和免疫抑制剂治疗。入院时，患者高热，左侧口腔肿胀疼痛。患者被诊断为口腔颌面部间隙感染（OMSI）。因此，随后对脓肿进行了局部切开、引流和冲洗。此外，停用了免疫抑制剂，减少了糖皮质激素剂量，并给予静脉抗生素治疗。患者1周后康复出院。值得注意的是，AAV的发病率极低。虽然OMSI并不罕见，但此前尚未有AAV合并OMSI同时发生的报道。据我们所知，这是首例AAV合并OMSI的报道病例。
