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The second HPV serology meeting: Progress and challenges in standardization of human papillomavirus serology assays.第二届 HPV 血清学会议：HPV 血清学检测标准化的进展与挑战。
Vaccine. 2023 Feb 3;41(6):1177-1181. doi: 10.1016/j.vaccine.2023.01.008. Epub 2023 Jan 13.
2
Spotlight on the 9-valent HPV vaccine.聚焦九价人乳头瘤病毒疫苗。
Drug Des Devel Ther. 2016 Dec 20;11:35-44. doi: 10.2147/DDDT.S91018. eCollection 2017.
3
Natural Acquired Immunity Against Subsequent Genital Human Papillomavirus Infection: A Systematic Review and Meta-analysis.针对后续生殖器人乳头瘤病毒感染的自然获得性免疫：一项系统评价与荟萃分析。
J Infect Dis. 2016 May 1;213(9):1444-54. doi: 10.1093/infdis/jiv753. Epub 2015 Dec 21.
4
Use of 9-valent human papillomavirus (HPV) vaccine: updated HPV vaccination recommendations of the advisory committee on immunization practices.九价人乳头瘤病毒（HPV）疫苗的使用：免疫实践咨询委员会的HPV疫苗接种最新建议
MMWR Morb Mortal Wkly Rep. 2015 Mar 27;64(11):300-4.
5
Risk of newly detected infections and cervical abnormalities in women seropositive for naturally acquired human papillomavirus type 16/18 antibodies: analysis of the control arm of PATRICIA.自然感染人乳头瘤病毒 16/18 型抗体阳性妇女新发感染和宫颈异常的风险：PATRICIA 对照臂分析。
J Infect Dis. 2014 Aug 15;210(4):517-34. doi: 10.1093/infdis/jiu139. Epub 2014 Mar 8.
6
Spotlight on quadrivalent human papillomavirus (types 6, 11, 16, 18) recombinant vaccine(Gardasil®) in the prevention of premalignant genital lesions, genital cancer, and genital warts in women.重点介绍四价人乳头瘤病毒（6、11、16、18 型）重组疫苗（佳达修®）在预防女性的癌前生殖器病变、生殖器癌和生殖器疣方面的作用。
BioDrugs. 2011 Oct 1;25(5):339-43. doi: 10.2165/11205060-000000000-00000.
7
Spotlight on AS04-adjuvanted human papillomavirus (HPV) types 16 and 18 vaccine (Cervarix®).聚焦 AS04 佐剂的人乳头瘤病毒（HPV）16 型和 18 型疫苗（佳达修®）。
BioDrugs. 2011 Aug 1;25(4):265-9. doi: 10.2165/11206830-000000000-00000.
8
Epidemiological study of anti-HPV16/18 seropositivity and subsequent risk of HPV16 and -18 infections.HPV16/18 型血清阳性的流行病学研究及其与 HPV16、-18 型感染后风险的关系。
J Natl Cancer Inst. 2010 Nov 3;102(21):1653-62. doi: 10.1093/jnci/djq384. Epub 2010 Oct 13.
9
Immunogenicity testing in human papillomavirus virus-like-particle vaccine trials.人乳头瘤病毒样颗粒疫苗试验中的免疫原性检测
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HPV 血清学实验室牵头开展了一项标准化和协调人乳头瘤病毒血清学检测的倡议。

The HPV Serology Laboratory leads an initiative to standardize and harmonize human papillomavirus serology assays.

机构信息

HPV Serology Laboratory, Frederick National Laboratory for Cancer Research, Frederick, Maryland, United States of America.

出版信息

PLoS Pathog. 2023 Jun 29;19(6):e1011403. doi: 10.1371/journal.ppat.1011403. eCollection 2023 Jun.

DOI:10.1371/journal.ppat.1011403
PMID:37384602
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10309594/
Abstract

The HPV Serology Laboratory is leading a global partnership initiative aiming for standardization and harmonization of current serology assay platforms being used to assess immune responses to HPV vaccines. Serology standardization is particularly important given the increasing number of immunobridging trials relying on serology data for approval of new vaccine dosing schedules or vaccine formulations. The initiative was established in 2017 to enable comparisons of data between different vaccines and relevant studies as well as expedite the implementation of new vaccines and vaccine indications. The HPV Serology Laboratory has held or attended several meetings with partnering laboratories, including international meetings in 2017, 2018, and 2021.

摘要

HPV 血清学实验室正在牵头一个全球合作倡议，旨在标准化和协调当前用于评估 HPV 疫苗免疫反应的血清学检测平台。鉴于越来越多的免疫桥接试验依赖血清学数据来批准新的疫苗剂量方案或疫苗配方，因此血清学标准化尤为重要。该倡议成立于 2017 年，旨在实现不同疫苗和相关研究之间的数据比较，并加速新疫苗和疫苗适应证的实施。HPV 血清学实验室已与合作实验室举行或参加了多次会议，包括 2017 年、2018 年和 2021 年的国际会议。