Park Se-Jun, Lee Chong-Suh, Park Jin-Sung, Shin Tae Soo, Kim Il Su, Kim Jeongkeun, Kang Kyung-Chung, Lee Keun-Ho
Department of Orthopedic Surgery, Spine Center, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, South Korea.
Department of Orthopedic Surgery, Haeundae Bumin Hospital, Busan, South Korea.
World Neurosurg. 2023 Sep;177:e554-e562. doi: 10.1016/j.wneu.2023.06.095. Epub 2023 Jun 27.
The present study assumed that the effects of deformity correction amounts on proximal junctional kyphosis (PJK) development after long deformity surgery would vary according to uppermost instrumented vertebrae (UIV) levels. Our study was to reveal the association between the amount of correction and PJK according to UIV levels.
Adult spinal deformity patients aged >50 years who underwent thoracolumbar fusion (≥4 levels) were included. PJK was defined by proximal junctional angles ≥15°. Presumed demographic and radiographic risk factors for PJK were evaluated including parameters regarding the correction amount such as postoperative change in lumbar lordosis and postoperative offset grouping, the value associated with age-adjusted pelvic incidence-lumbar lordosis mismatch. The patients were divided according to UIV levels of T10 or above (group A) and T11 or below (group B). Multivariate analyses were performed separately for both groups.
The present study included 241 patients (74 for group A and 167 for group B). PJK developed in approximately half of all patients within an average of 5 years of follow-up. For group A, only body mass index (P = 0.002) was associated with PJK. No radiographic parameters were correlated. For group B, postoperative change in lumbar lordosis (P = 0.009) and offset value (P = 0.030) were significant risk factors for PJK development.
The correction amount of sagittal deformity increased the risk of PJK only in patients with UIV at or below T11. However, it was not associated with PJK development in patients with UIV at or above T10.
本研究假设,在长节段畸形手术之后,畸形矫正量对近端交界性后凸(PJK)发生的影响会因最上位固定椎体(UIV)的水平不同而有所差异。我们的研究旨在揭示根据UIV水平,矫正量与PJK之间的关联。
纳入年龄大于50岁、接受胸腰段融合术(≥4个节段)的成人脊柱畸形患者。PJK定义为近端交界角≥15°。评估PJK的假定人口统计学和影像学风险因素,包括与矫正量相关的参数,如术后腰椎前凸的变化和术后偏移分组,以及与年龄调整后的骨盆入射角-腰椎前凸失配相关的值。患者根据UIV水平分为T10及以上组(A组)和T11及以下组(B组)。对两组分别进行多变量分析。
本研究共纳入241例患者(A组74例,B组167例)。在平均5年的随访期内,约半数患者发生了PJK。对于A组,只有体重指数(P = 0.002)与PJK相关。没有影像学参数与之相关。对于B组,术后腰椎前凸的变化(P = 0.009)和偏移值(P = 0.030)是PJK发生的显著风险因素。
矢状面畸形的矫正量仅在UIV为T11及以下的患者中增加了PJK的风险。然而,在UIV为T10及以上的患者中,它与PJK的发生无关。