致幻剂和相关药物治疗作为姑息治疗中老年患者的整合医学。

Psychedelics and Related Pharmacotherapies as Integrative Medicine for Older Adults in Palliative Care.

机构信息

Department of Psychiatry, Brigham and Women's Hospital, 60 Fenwood Road, Boston, MA 02115, USA; Harvard Medical School.

Division of Palliative Care, Emory University, 1821 Clifton Road, NE, Suite 1017, Atlanta, GA 30329, USA.

出版信息

Clin Geriatr Med. 2023 Aug;39(3):423-436. doi: 10.1016/j.cger.2023.04.004. Epub 2023 May 12.

DOI:10.1016/j.cger.2023.04.004

PMID:37385694

Abstract

Psychological distress at the end of life is a common experience that lacks effective treatments. This is in part due to the multidimensional nature of psychological distress at the end of life, encompassing an interplay between psychosocial and existential distress as well as physical symptom burden. Research shows that psychedelic-assisted therapy is an effective treatment of end of life distress. Ketamine and cannabis may help with quick and effective treatment of symptom burden at the end of life. Although these novel interventions show promise, further data is needed, particularly in elderly populations.

摘要

生命末期的心理困扰是一种常见的体验，缺乏有效的治疗方法。这在一定程度上是由于生命末期的心理困扰具有多维性，包括心理社会和存在困扰以及身体症状负担之间的相互作用。研究表明，迷幻辅助疗法是治疗生命末期困扰的有效方法。氯胺酮和大麻可能有助于快速有效地治疗生命末期的症状负担。尽管这些新的干预措施显示出了希望，但还需要更多的数据，特别是在老年人群体中。