Dooley D P, Mills G M, Spiva D A
South Med J. 1986 Aug;79(8):1044-5. doi: 10.1097/00007611-198608000-00036.
We have described a patient with simultaneous onset of antibody-positive immune thrombocytopenic purpura and ulcerative colitis, an association that must be extremely rare. Although the colitis responded to steroid therapy, the thrombocytopenia required splenectomy. The antibody was monomeric, with HLA specificity against A3 and B8 platelets.
我们描述了一名同时发生抗体阳性免疫性血小板减少性紫癜和溃疡性结肠炎的患者,这种关联肯定极为罕见。尽管结肠炎对类固醇治疗有反应,但血小板减少症需要进行脾切除术。该抗体为单体,对A3和B8血小板具有HLA特异性。