[Cardiospecific enzyme activity and clinical significance of the parameters of blood enzymograms in the acute phase of myocardial infarction].

Serial investigations of the activity of cardiospecific enzymes in the blood allowed one to reveal a prolonged type of a dynamic curve "enzymatic activity-time" characterized by two or more peaks in 66.7% of patients with the acute phase of myocardial infarction. It was assumed that such a curve type could be determined by the formation of multiple necrotic foci in the myocardium. A close correlation between the rate of increment and peak activity of the LDH, CPK and MB-CPK was shown. These and other parameters of the blood enzymogram in the acute phase of myocardial infarction made it possible to assess the development of a necrotic process in the myocardium and, consequently, a clinical course of disease.