消除复杂脊柱畸形（CVM）携带者和波兰荷斯坦-弗里生公牛。
Eradication of carriers of Complex Vertebral Malformation (CVM) and in Polish Holstein-Friesian bulls.
机构信息
University of Warmia and Mazury, Department of Animal Genetics, Faculty of Animal Bioengineering, Oczapowskiego 5, 10-719 Olsztyn, Poland.
出版信息
Pol J Vet Sci. 2023 Jun;26(2):315-317. doi: 10.24425/pjvs.2023.145031.
CVM ( ) and (BY) are the most common autosomal recessive genetic defects occurring in the last two decades in Holstein dairy cattle around the world. Beginning from 2004 and 2014, 3035 and 338 Polish Holstein-Friesian bulls were tested to find carriers of CVM and BY, respectively. Among analyzed bulls 191 CVM carriers (6.29%) and 20 BY carriers (5.92%) were identified. No CVM carriers were observed beginning from 2016, whereas only single BY carriers was identified annually for the last 5 years. One bull turned to be double CVM/ BY carrier as a son of also double CVM/BY top Dutch sire (JABOT 90676-4-9). It is shown that CVM and BY defects are practically eradicated from Polish dairy cattle although incidental testing should be continued if new bulls with CVM or BY carriers in sire or dam pedigree will unexpectedly appear.
CVM（软骨发育不全症）和 BY（β-乳球蛋白缺乏症）是过去二十年来全世界荷斯坦奶牛最常见的两种常染色体隐性遗传缺陷。从 2004 年至 2014 年，对 3035 头和 338 头波兰荷斯坦奶牛公牛进行了 CVM 和 BY 携带者的检测。在分析的公牛中，发现了 191 名 CVM 携带者（6.29%）和 20 名 BY 携带者（5.92%）。自 2016 年以来未发现 CVM 携带者，而在过去的 5 年中，每年仅发现 1 名 BY 携带者。一头公牛是双重 CVM/BY 携带者，其父亲也是双重 CVM/BY 的荷兰顶级种公牛（JABOT 90676-4-9）的儿子。结果表明，尽管应该继续进行偶然检测，但 CVM 和 BY 缺陷实际上已从波兰奶牛中消除，如果在公牛或母牛血统中出现具有 CVM 或 BY 携带者的新公牛，就会出现意外情况。
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