Department of Obstetrics and Gynecology, Alpert Medical School, Brown University, Providence, RI, USA.
Department of Obstetrics, Gynecology and Reproductive Sciences, McGovern Medical School, The University of Texas Health Science Center at Houston, Houston, TX, USA.
Arch Gynecol Obstet. 2024 Jun;309(6):2421-2426. doi: 10.1007/s00404-023-07113-6. Epub 2023 Jun 30.
We hypothesized that among obese patients with a history of cesarean birth, a TOLAC is associated with decreased composite maternal adverse outcomes (CMAO) compared to planned repeat low transverse cesarean section (RLTCS).
In this population-based cross-sectional study using the National Birth Certificate database from 2016 to 2020, we compared obese patients who attempted TOLAC at term (≥ 37 weeks estimated gestational age) to planned RLTCS. The primary outcome was a CMAO, defined as delivery complications, including intensive care unit (ICU) admission, uterine rupture, unplanned hysterectomy, or maternal blood transfusion.
Overall, 794,278 patients met inclusion criteria for the study; 126,809 underwent a TOLAC, and 667,469 had a planned RLTCS. The overall CMAO was significantly higher for patients undergoing TOLAC (9.0 per 1000 live births) compared to RLTCS (5.3 per 1000 live births; aRR 1.64, 95% CI 1.53-1.75).
This data demonstrate that in obese patients with prior cesarean birth, a trial of labor is associated with increased maternal morbidity when compared to a planned repeat cesarean birth.
我们假设,在有剖宫产史的肥胖患者中,与计划性再次行剖宫产(RLTCS)相比,试产(TOLAC)与复合产妇不良结局(CMAO)减少相关。
本研究采用 2016 年至 2020 年全国出生证明数据库进行基于人群的横断面研究,比较了在足月(≥37 周估计胎龄)尝试 TOLAC 的肥胖患者与计划性 RLTCS 的患者。主要结局为复合产妇不良结局,包括入住重症监护病房(ICU)、子宫破裂、非计划性子宫切除术或产妇输血。
总体而言,有 794278 名患者符合研究纳入标准;其中 126809 例行 TOLAC,667469 例行计划性 RLTCS。与 RLTCS(5.3/1000 活产)相比,TOLAC 患者的总体 CMAO 明显更高(9.0/1000 活产;ARR 1.64,95%CI 1.53-1.75)。
本数据表明,与计划性再次剖宫产相比,在有剖宫产史的肥胖患者中,试产与产妇发病率增加相关。