Laboratory for Neurorehabilitation Science, Medicine Section, Faculty of Science and Medicine, University of Fribourg, 1700, Fribourg, Switzerland.
UniDistance Suisse, Schinerstrasse 18, 3900, Brigue, Switzerland.
Sci Rep. 2023 Jun 30;13(1):10659. doi: 10.1038/s41598-023-36859-x.
The overvaluation of high-energy, palatable food cues contributes to unhealthy eating and being overweight. Reducing the valuation of unhealthy food may thus constitute a powerful lever to improve eating habits and conditions characterized by unhealthy eating. We conducted a double-blind, placebo-controlled, randomized intervention trial assessing the efficacy of a five to twenty days online cognitive training intervention to reduce sugary drink perceived palatability and consumption. Our intervention involved a recently identified action-to-valuation mechanism of action, in which the repeated inhibition of prepotent motor responses to hedonic food cues in a Go/NoGo (GNG) and an attentional bias modification (ABM) task eventually reduces their valuation and intake. Confirming our hypotheses, the experimental intervention with consistent (100%) mapping between motor inhibition and the targeted unhealthy sugary drinks cues induced a larger decrease in their valuation than the control intervention with inconsistent (50%) mapping (- 27.6% vs. - 19%), and a larger increase of the (water) items associated with response execution (+ 11% vs + 4.2%). Exploratory analyses suggest that the effect of training on unhealthy items valuation may persist for at least one month. Against our hypothesis, we observed equivalent reductions in self-reported consumption of sugary drinks following the two interventions (exp: - 27% vs. ctrl: - 19%, BF = 4.7), suggesting a dose-independent effect of motor inhibition on self-reported consumption. Our collective results corroborate the robustness and large size of the devaluation effects induced by response inhibition on palatable items, but challenge the assumption of a linear relationship between such effects and the actual consumption of the target items. PROTOCOL REGISTRATION: The stage 1 protocol for this Registered Report was accepted in principle on 30/03/2021. The protocol, as accepted by the journal, can be found at: https://doi.org/10.17605/OSF.IO/5ESMP .
高能量、美味食物线索的高估导致了不健康的饮食和超重。因此,降低不健康食物的估值可能是改善饮食习惯和不健康饮食状况的有力杠杆。我们进行了一项双盲、安慰剂对照、随机干预试验,评估了为期五到二十天的在线认知训练干预减少含糖饮料感知美味和消费的效果。我们的干预措施涉及到最近确定的一种作用于价值的作用机制,即在 Go/NoGo(GNG)和注意力偏差修正(ABM)任务中,反复抑制对享乐性食物线索的优势运动反应,最终降低它们的价值和摄入量。证实了我们的假设,与控制干预(不一致映射:50%)相比,实验干预(一致映射:100%)对目标不健康含糖饮料线索的运动抑制与价值降低之间具有更强的相关性,导致其价值降低更大(-27.6% 比-19%),与反应执行相关的(水)项目增加更大(+11% 比+4.2%)。探索性分析表明,训练对不健康项目估值的影响可能至少持续一个月。与我们的假设相反,我们观察到两种干预措施后自我报告的含糖饮料消费都有同等程度的减少(实验:-27%,对照:-19%,BF=4.7),表明运动抑制对自我报告消费的影响与剂量无关。我们的集体结果证实了对美味项目的反应抑制所产生的估值效应的稳健性和大效应,但挑战了这种效应与目标项目实际消费之间的线性关系的假设。方案注册:本注册报告的第一阶段方案于 2021 年 3 月 30 日原则上被接受。可在以下网址找到该方案:https://doi.org/10.17605/OSF.IO/5ESMP。