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单次注射神经阻滞在全膝关节置换术中的应用:股神经阻滞与股三角阻滞和收肌管阻滞的随机对照双盲试验。

Single-injection nerve blocks for total knee arthroplasty: femoral nerve block versus femoral triangle block versus adductor canal block-a randomized controlled double-blinded trial.

机构信息

Anesthesiology and Reanimation Department, Vall d'Hebron University Hospital, Universitat Autònoma de Barcelona, Barcelona, Spain.

Physical Medicine and Rehabilitation Department, Vall d'Hebron University Hospital, Universitat Autònoma de Barcelona, Barcelona, Spain.

出版信息

Arch Orthop Trauma Surg. 2023 Nov;143(11):6763-6771. doi: 10.1007/s00402-023-04960-5. Epub 2023 Jun 30.

Abstract

INTRODUCTION

Femoral nerve block (FNB) is a well-established analgesic technique for TKA. However, it associates quadriceps weakness. Therefore, femoral triangle block (FTB) and adductor canal block (ACB) were proposed as effective alternative motor-spearing techniques. The primary objective was to compare quadriceps muscle strength preservation between FNB, FTB and ACB in TKA. The secondary objective was to analyze pain control and functional outcomes.

METHODS

This is a prospective, double-blinded RCT. From April 2018 to April 2019, patients who undergo a primary TKA were randomized into three experimental groups: FNB-G1/FTB-G2/ACB-G3. Quadriceps strength preservation was measured as the difference in maximum voluntary isometric contraction (MVIC) preoperatively and postoperatively.

RESULTS

Seventy-eight patients (G1, n = 22; G2, n = 26; G3, n = 30) met our inclusion/exclusion criteria. Patients with FNB retained significantly lower baseline MVIC at 6 h postoperatively (p = 0.001), but there were no differences at 24 and 48 h. There were no differences between the groups in functional outcomes at any time point. Patients in the FNB-G1 presented significant lower pain scores at 6 h (p = 0.01), 24 h (p = 0.005) and 48 h (p = 0.01). The highest cumulative opioid requirement was reported in ACB-G3.

CONCLUSION

For patients undergoing TKA, FTB and ACB preserve quadriceps strength better than FNB at 6 h postoperatively, but there are no differences at 24 and 48 h. Moreover, this early inferiority does not translate to worse functional outcomes at any time point. FNB is associated with better pain control at 6, 24 and 48 h after surgery, while ACB presents the highest cumulative opioid requirement.

CLINICAL TRIAL REGISTRATION

This study was registered in clinicaltrials.gov (NCT03518450; https://clinicaltrials.gov/ct2/show/NCT03518450 ; submitted March 17, 2018).

摘要

引言

股神经阻滞(FNB)是一种成熟的 TKA 镇痛技术,但它与股四头肌无力有关。因此,股三角阻滞(FTB)和收肌管阻滞(ACB)被提出作为有效的、不影响运动功能的替代技术。主要目的是比较 FNB、FTB 和 ACB 在 TKA 中对股四头肌肌力的保护作用。次要目的是分析疼痛控制和功能结果。

方法

这是一项前瞻性、双盲 RCT。2018 年 4 月至 2019 年 4 月,接受初次 TKA 的患者被随机分为三组实验组:FNB-G1/FTB-G2/ACB-G3。股四头肌肌力保护作用通过术前和术后最大自主等长收缩(MVIC)的差值来测量。

结果

78 例患者(G1 组,n=22;G2 组,n=26;G3 组,n=30)符合纳入/排除标准。FNB 组患者术后 6 小时 MVIC 保留明显较低(p=0.001),但在 24 小时和 48 小时时无差异。在任何时间点,三组患者的功能结果均无差异。FNB-G1 组患者在术后 6 小时(p=0.01)、24 小时(p=0.005)和 48 小时(p=0.01)时疼痛评分明显较低。ACB-G3 组患者的累积阿片类药物需求最高。

结论

对于接受 TKA 的患者,FTB 和 ACB 在术后 6 小时时比 FNB 更好地保留股四头肌肌力,但在 24 小时和 48 小时时无差异。此外,这种早期劣势在任何时间点都不会转化为更差的功能结果。FNB 在术后 6、24 和 48 小时时疼痛控制更好,而 ACB 呈现最高的累积阿片类药物需求。

临床试验注册

本研究在 clinicaltrials.gov 注册(NCT03518450;https://clinicaltrials.gov/ct2/show/NCT03518450;于 2018 年 3 月 17 日提交)。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/aeec/10542711/bf790da1cf01/402_2023_4960_Fig1_HTML.jpg

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