South Western Sydney Clinical School, Faculty of Medicine, University of New South Wales, Sydney, Australia.
Department of Anaesthesia, Royal Prince Alfred Hospital, Sydney, Australia.
Br J Anaesth. 2019 Sep;123(3):360-367. doi: 10.1016/j.bja.2019.03.021. Epub 2019 May 2.
Adductor canal (AC) catheters are being used to provide continuous postoperative analgesia after total knee arthroplasty (TKA) surgery. There are anatomical arguments that most AC catheters are being inserted into the femoral triangle (FT) compartment of the thigh rather than the AC compartment. The clinical relevance of this is unknown with respect to motor weakness, quality of analgesia, and opioid consumption. We hypothesised that AC catheters provide superior functional mobilisation on postoperative Day 1 after TKA as measured using the Timed Up and Go (TUG) test.
In this multinational, multicentre, double-blinded RCT, catheters were inserted under ultrasound guidance into the anatomical AC and FT compartments. The standardised protocol included spinal anaesthesia without intrathecal morphine, fixed catheter infusion rates, and oral analgesia.
Of 151 subjects recruited, 75 were in the AC group and 76 in the FT group. There was no statistically significant difference in TUG on postoperative Day 1 between AC (38 [29-55] s) and FT subjects (44 [32-64] s) (median [inter-quartile range]); P=0.11). There was no difference in TUG Day 2, AC (38 [27-53] s) vs FT (42 [31-59] s); P=0.66. There were no statistically significant differences for secondary endpoints of pain level, effectiveness of pain relief, interference of functional activities and interpersonal relationships by pain, and opioid consumption between groups.
There were no differences in immediate postoperative functional mobility, analgesia, and opioid consumption provided by catheters inserted into the AC vs FT locations for TKA surgery.
ANZCTR12617001421325.
股管(AC)导管被用于提供全膝关节置换术(TKA)术后的连续术后镇痛。从解剖学角度来看,大多数 AC 导管被插入大腿的股三角(FT)间隙而不是 AC 间隙。然而,这在运动无力、镇痛质量和阿片类药物消耗方面的临床相关性尚不清楚。我们假设,与 FT 组相比,AC 导管在 TKA 术后第 1 天提供更好的功能活动能力,这可以通过计时起立行走(TUG)测试来衡量。
在这项多中心、双盲 RCT 中,导管在超声引导下插入解剖学上的 AC 和 FT 间隙。标准化方案包括无鞘内吗啡的脊髓麻醉、固定导管输注率和口服镇痛。
在招募的 151 名受试者中,75 名在 AC 组,76 名在 FT 组。AC 组(38 [29-55] 秒)和 FT 组(44 [32-64] 秒)在术后第 1 天的 TUG 上没有统计学上的显著差异(中位数 [四分位距]);P=0.11)。第 2 天的 TUG 也没有差异,AC 组(38 [27-53] 秒)vs FT 组(42 [31-59] 秒);P=0.66。两组之间在次要终点(疼痛水平、镇痛效果、功能活动和人际关系受疼痛的干扰以及阿片类药物消耗)方面也没有统计学上的显著差异。
在 TKA 手术中,将导管插入 AC 与 FT 位置在术后即刻的功能活动、镇痛和阿片类药物消耗方面没有差异。
ANZCTR12617001421325。