Dr Anindita Datta, Associate Professor, Department of Radiology and Imaging, Bangabandhu Sheikh Mujib Medical University (BSMMU), Dhaka, Bangladesh; E-mail:
Mymensingh Med J. 2023 Jul;32(3):823-832.
Following the COVID-19 pandemic, a growing percentage of COVID-19 survivors exhibit post-COVID symptoms. This cross-sectional study aimed to assess radiological findings in individuals having post-COVID respiratory problems. This study was conducted in the Departments of Radiology and Imaging and Internal Medicine, Bangabandhu Sheikh Mujib Medical University (BSMMU), Dhaka, Bangladesh from November 2021 to June 2022 and included 30 COVID survivors aged 40 to 65 years. We employed a pre-tested semi-structured questionnaire including socio-demographic information, clinical data and CT chest imaging parameters. Pearson's correlation coefficient was calculated, as well as multiple linear regressions. Among 30 participants, 56.0% were male. The mean age of the respondents was 51.20 years (standard deviation of 7.09), ranging from 40 to 65 years. Approximately one-third of the participants had at least one co-morbid condition where hypertension (26.67%), diabetes (26.67%), chronic interstitial lung disease (16.67%) and obesity (16.67%) were most commonly recorded. Approximately 20.0% of participants were smokers. The incident of at least one post-COVID symptom was 100.0%. Approximately 73.0% presented with post-COVID lethargy, 16.67% with SoB (Shortness of Breath), and 90.0% of participants complaint of self-reported anxiety. We have found a positive correlation between age and overall lung involvement. The most common lung tomographic findings were fibrosis (93.0%) and diffuse ground glass opacity (70.0%). Interstitial lung thickening was found in 50.0% of cases and bronchiectasis accounted for 16.67%. In 6.6% of cases, there was no pulmonary lesion. It was notifiable that, with time, the feature of DGGO (diffuse ground glass opacity) became subtle and the total lung involvement decreased from 75.0% to about 25.0% during the post-COVID period. Timely assessment for post-COVID pulmonary sequelae by high-resolution CT chest scan might play an important role in modulating a treatment plan for patients suffering from the post-COVID syndrome.
在 COVID-19 大流行之后，越来越多的 COVID-19 幸存者出现了 COVID-19 后症状。本横断面研究旨在评估有 COVID-19 后呼吸问题的个体的放射学发现。本研究于 2021 年 11 月至 2022 年 6 月在孟加拉国达卡的班加班杜谢赫·穆吉布医科大学（BSMMU）放射科和内科影像学系进行，纳入了 30 名年龄在 40 至 65 岁之间的 COVID 幸存者。我们使用了一份经过预测试的半结构式问卷，其中包括社会人口统计学信息、临床数据和 CT 胸部成像参数。计算了 Pearson 相关系数和多元线性回归。在 30 名参与者中，56.0%为男性。受访者的平均年龄为 51.20 岁（标准差为 7.09），年龄在 40 至 65 岁之间。大约三分之一的参与者至少有一种合并症，其中高血压（26.67%）、糖尿病（26.67%）、慢性间质性肺病（16.67%）和肥胖症（16.67%）最为常见。大约 20.0%的参与者是吸烟者。至少有一种 COVID-19 后症状的发生率为 100.0%。大约 73.0%的人出现 COVID-19 后乏力，16.67%的人出现呼吸急促（SoB），90.0%的参与者自诉有焦虑。我们发现年龄与整体肺部受累呈正相关。最常见的肺部 CT 表现为纤维化（93.0%）和弥漫性磨玻璃影（70.0%）。间质性肺增厚见于 50.0%的病例，支气管扩张占 16.67%。在 6.6%的病例中，没有肺部病变。值得注意的是，随着时间的推移，DGGO（弥漫性磨玻璃影）的特征变得不明显，COVID-19 后期间总肺受累从 75.0%降至约 25.0%。通过高分辨率 CT 胸部扫描及时评估 COVID-19 后肺部后遗症可能对调整 COVID-19 后综合征患者的治疗计划发挥重要作用。
