Vagner R I, Kuchava V O, Pozharisskiĭ K M
Vopr Onkol. 1986;32(7):30-5.
The paper discusses the results of a histologic study of intrathoracic lymph nodes removed during surgery for lung cancer in 621 cases at different stages of metastatic spread. The gross appearance of some lymph nodes did not match their real histologic pattern: about 36% of grossly-identifiable metastatic nodes were microscopically shown to be intact whereas about 12% of grossly normal lymph nodes proved to be involved, particularly in cases of adenocarcinoma. Most of the enlarged and compact lymph nodes in cases of low-differentiated lung carcinoma revealed metastases. Intraoperative biopsy of intrathoracic lymph nodes followed by microscopy serves as a highly-predictive procedure in assessing the extent of regional dissemination of lung cancer.
本文讨论了对621例处于不同转移扩散阶段的肺癌患者在手术中切除的胸内淋巴结进行组织学研究的结果。一些淋巴结的大体外观与其实际组织学模式不相符：约36%在大体上可识别为转移的淋巴结在显微镜下显示并无转移，而约12%大体正常的淋巴结在显微镜下证实已发生转移，尤其是在腺癌病例中。低分化肺癌病例中大多数肿大且致密的淋巴结显示有转移。胸内淋巴结术中活检并进行显微镜检查是评估肺癌区域播散范围的一项具有高度预测性的操作。
