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过敏和血管性水肿的模拟物:鲭鱼中毒、肥大细胞活化障碍和遗传性α-胰蛋白酶血症。

Mimics of Allergy and Angioedema: Scombroid, Mast Cell Activation Disorders, and Hereditary Alpha Tryptasemia.

机构信息

Department of Emergency Medicine, Ochsner Medical Center, 1514 Jefferson Highway, Jefferson, New Orleans, LA 70121, USA.

Department of Emergency Medicine, Ochsner Medical Center, 1514 Jefferson Highway, Jefferson, New Orleans, LA 70121, USA.

出版信息

Immunol Allergy Clin North Am. 2023 Aug;43(3):553-568. doi: 10.1016/j.iac.2022.10.007.

Abstract

Scombroid poisoning, systemic mastocytosis, and hereditary alpha tryptasemia all present with episodes that resemble allergic reactions. Knowledge regarding systemic mastocytosis and hereditary alpha tryptasemia is quickly evolving. Epidemiology, pathophysiology, and strategies to identify and diagnose are discussed. Evidence-based management in the emergency setting and beyond is also explored and summarized. Key differences are described between these events and allergic reactions.

摘要

鲭鱼中毒、系统性肥大细胞增多症和遗传性α-胰蛋白酶血症均表现为类似于过敏反应的发作。关于系统性肥大细胞增多症和遗传性α-胰蛋白酶血症的知识正在迅速发展。本文讨论了流行病学、病理生理学以及识别和诊断策略。还探讨和总结了在急诊环境内外的基于证据的管理。描述了这些事件与过敏反应之间的关键差异。

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