Department of Orthopaedic Surgery, Atrium Health Musculoskeletal Institute, Charlotte, North Carolina.
Department of Orthopaedic Surgery, Atrium Health Musculoskeletal Institute, Charlotte, North Carolina.
Injury. 2023 Aug;54(8):110872. doi: 10.1016/j.injury.2023.110872. Epub 2023 Jun 14.
To determine if the use of Peripheral Nerve Block (PNB) versus Local Infiltration Analgesia (LIA) for hip fracture patients, affected opioid consumption in the early post-operative period.
Retrospective cohort study SETTING: Two level 1 trauma centers PATIENTS/INTERVENTION: 588 patients with surgically treated AO/OTA 31A and 31B fractures between February 2016-October 2017 were included. 415 (70.6%) received general anesthesia (GA) alone, 152 received GA plus perioperative PNB (25.9%), and 21 had GA plus LIA intra-operatively (3.6%). Median age was 82 years; predominantly female (67%) and AO/OTA 31A fractures (55.37%).
Morphine Milligram Equivalents (MME) at 24 and 48 hours postoperatively, length of stay (LOS) and the occurrence of any complication after surgery RESULTS: The PNB cohort was less likely to use any opioid than the GA group at 24 and 48 hours postoperatively (OR: 0.36, 95% CI: 0.22-0.61 and OR: 0.56, 95% CI: 0.35-0.89 respectively). LOS ≥ 10 days had 3.24 times the odds of 24- and 48-hour opioid administration compared to LOS ≤ 10 days (OR: 3.24, 95% CI 1.11-9.42; OR: 2.98, 95% CI 1.38-6.41, respectively). The most common complication was post-operative delirium, with PNB more likely to present with any complication compared to GA (OR= 1.88, 95% CI 1.09-3.26). There was no difference when comparing LIA to general anesthesia.
Our findings suggest PNB for hip fracture can help limit the use of post-operative opioids with adequate pain relief. Regional analgesia does not seem to avoid complications such as delirium.
确定在接受髋关节骨折手术的患者中,使用外周神经阻滞(PNB)与局部浸润镇痛(LIA)相比,对术后早期阿片类药物的消耗是否有影响。
回顾性队列研究
两个 1 级创伤中心
患者/干预措施:2016 年 2 月至 2017 年 10 月期间,共纳入 588 例接受手术治疗的 AO/OTA 31A 和 31B 骨折患者。其中 415 例(70.6%)接受单纯全身麻醉(GA),152 例接受 GA 加围手术期 PNB(25.9%),21 例术中接受 GA 加 LIA(3.6%)。中位年龄为 82 岁;女性居多(67%),AO/OTA 31A 骨折(55.37%)。
术后 24 和 48 小时吗啡毫克当量(MME),住院时间(LOS)和术后任何并发症的发生情况。
与 GA 组相比,PNB 组在术后 24 和 48 小时使用任何阿片类药物的可能性均较低(OR:0.36,95%CI:0.22-0.61 和 OR:0.56,95%CI:0.35-0.89)。LOS≥10 天与 LOS≤10 天相比,24 小时和 48 小时使用阿片类药物的可能性增加 3.24 倍(OR:3.24,95%CI 1.11-9.42;OR:2.98,95%CI 1.38-6.41)。最常见的并发症是术后谵妄,与 GA 相比,PNB 更有可能出现任何并发症(OR=1.88,95%CI 1.09-3.26)。与 GA 相比,LIA 没有差异。
我们的研究结果表明,髋关节骨折患者使用 PNB 可有助于限制术后阿片类药物的使用,同时获得足够的疼痛缓解。区域镇痛似乎并不能避免谵妄等并发症。