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手术治疗的髋部骨折患者中,麻醉选择对术后疼痛管理的影响。

Impact of Anesthesia selection on Post-Op Pain Management in Operatively treated Hip Fractures.

机构信息

Department of Orthopaedic Surgery, Atrium Health Musculoskeletal Institute, Charlotte, North Carolina.

Department of Orthopaedic Surgery, Atrium Health Musculoskeletal Institute, Charlotte, North Carolina.

出版信息

Injury. 2023 Aug;54(8):110872. doi: 10.1016/j.injury.2023.110872. Epub 2023 Jun 14.

Abstract

OBJECTIVES

To determine if the use of Peripheral Nerve Block (PNB) versus Local Infiltration Analgesia (LIA) for hip fracture patients, affected opioid consumption in the early post-operative period.

DESIGN

Retrospective cohort study SETTING: Two level 1 trauma centers PATIENTS/INTERVENTION: 588 patients with surgically treated AO/OTA 31A and 31B fractures between February 2016-October 2017 were included. 415 (70.6%) received general anesthesia (GA) alone, 152 received GA plus perioperative PNB (25.9%), and 21 had GA plus LIA intra-operatively (3.6%). Median age was 82 years; predominantly female (67%) and AO/OTA 31A fractures (55.37%).

MAIN OUTCOME MEASURES

Morphine Milligram Equivalents (MME) at 24 and 48 hours postoperatively, length of stay (LOS) and the occurrence of any complication after surgery RESULTS: The PNB cohort was less likely to use any opioid than the GA group at 24 and 48 hours postoperatively (OR: 0.36, 95% CI: 0.22-0.61 and OR: 0.56, 95% CI: 0.35-0.89 respectively). LOS ≥ 10 days had 3.24 times the odds of 24- and 48-hour opioid administration compared to LOS ≤ 10 days (OR: 3.24, 95% CI 1.11-9.42; OR: 2.98, 95% CI 1.38-6.41, respectively). The most common complication was post-operative delirium, with PNB more likely to present with any complication compared to GA (OR= 1.88, 95% CI 1.09-3.26). There was no difference when comparing LIA to general anesthesia.

CONCLUSIONS

Our findings suggest PNB for hip fracture can help limit the use of post-operative opioids with adequate pain relief. Regional analgesia does not seem to avoid complications such as delirium.

摘要

目的

确定在接受髋关节骨折手术的患者中,使用外周神经阻滞(PNB)与局部浸润镇痛(LIA)相比,对术后早期阿片类药物的消耗是否有影响。

设计

回顾性队列研究

设置

两个 1 级创伤中心

患者/干预措施:2016 年 2 月至 2017 年 10 月期间,共纳入 588 例接受手术治疗的 AO/OTA 31A 和 31B 骨折患者。其中 415 例(70.6%)接受单纯全身麻醉(GA),152 例接受 GA 加围手术期 PNB(25.9%),21 例术中接受 GA 加 LIA(3.6%)。中位年龄为 82 岁;女性居多(67%),AO/OTA 31A 骨折(55.37%)。

主要观察指标

术后 24 和 48 小时吗啡毫克当量(MME),住院时间(LOS)和术后任何并发症的发生情况。

结果

与 GA 组相比,PNB 组在术后 24 和 48 小时使用任何阿片类药物的可能性均较低(OR:0.36,95%CI:0.22-0.61 和 OR:0.56,95%CI:0.35-0.89)。LOS≥10 天与 LOS≤10 天相比,24 小时和 48 小时使用阿片类药物的可能性增加 3.24 倍(OR:3.24,95%CI 1.11-9.42;OR:2.98,95%CI 1.38-6.41)。最常见的并发症是术后谵妄,与 GA 相比,PNB 更有可能出现任何并发症(OR=1.88,95%CI 1.09-3.26)。与 GA 相比,LIA 没有差异。

结论

我们的研究结果表明,髋关节骨折患者使用 PNB 可有助于限制术后阿片类药物的使用,同时获得足够的疼痛缓解。区域镇痛似乎并不能避免谵妄等并发症。

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