轮状病毒相关性轻度胃肠炎伴良性惊厥患儿的临床特征及随访
Clinical characteristics and follow-up of children with norovirus-associated benign convulsions with mild gastroenteritis.
机构信息
Department of Neurology, Guangzhou Women and Children's Medical Center, Guangzhou, China.
Department of Emergency, Guangzhou Women and Children's Medical Center, Guangzhou, China.
出版信息
Epilepsia Open. 2023 Sep;8(3):1049-1053. doi: 10.1002/epi4.12782. Epub 2023 Jul 11.
OBJECTIVE
Explore the clinical characteristics and prognosis of children with norovirus (NoV)-associated benign convulsions with mild gastroenteritis (CwG).
METHODS
We retrospectively analyzed the Clinical and laboratory data of children with NoV-associated CwG admitted to the emergency department of Guangzhou Children's Hospital between January 2019 and January 2020. And patients were followed up for 23-36 months.
RESULTS
There are 49 cases met the CwG criteria. Vomiting was the first symptom in 31 (63.3%) patients, and vomiting could be the main or the only gastrointestinal symptom. The mean frequency of seizures was 3.8 ± 2.4 episodes. Most patients (95.9%) experienced seizures that lasted for less than 5 min. Of the 43 (87.8%) cases followed up from 23 to 36 months, only one experienced recurrent convulsions (after rotavirus infection).
SIGNIFICANCE
NoV-associated CwG patients were prone to experiencing more convulsions. However, because most NoV-associated CwG patients had good prognosis, long-term use of anticonvulsants are unnecessary.
目的
探讨诺如病毒（NoV）相关轻症胃肠炎伴良性婴幼儿惊厥（CwG）患儿的临床特征和预后。
方法
回顾性分析 2019 年 1 月至 2020 年 1 月广州儿童医院急诊科收治的符合 NoV 相关 CwG 标准的患儿的临床和实验室资料。并对患者进行了 23-36 个月的随访。
结果
符合 CwG 标准的患儿有 49 例。31 例（63.3%）患儿以呕吐为首发症状，且呕吐可作为唯一或主要胃肠道症状。惊厥的平均发作频率为 3.8±2.4 次。大多数患儿（95.9%）的惊厥持续时间小于 5 min。43 例（87.8%）随访 23-36 个月的患儿中，仅 1 例患儿（轮状病毒感染后）出现复发惊厥。
意义
NoV 相关 CwG 患儿易发生多次惊厥，但由于大多数 NoV 相关 CwG 患儿预后良好，长期使用抗惊厥药物并无必要。
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