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小儿自发性脑脊液漏修复:内镜经鼻内入路。

Pediatric Spontaneous Cerebrospinal Fluid Leak Repair: An Endoscopic Endonasal Approach.

机构信息

School of Medicine and Health Sciences, TecSalud, Monterrey, Mexico.

Division of Pediatric Otolaryngology, Children's Hospital Los Angeles, Los Angeles, CA, USA.

出版信息

Ear Nose Throat J. 2023 Sep;102(9_suppl):40S-42S. doi: 10.1177/01455613231184959. Epub 2023 Jul 3.

Abstract

Spontaneous cerebrospinal fluid (CSF) rhinorrhea in the pediatric population is an exceedingly rare condition that occurs when the dura mater is breached, resulting in CSF drainage from the subarachnoid space into surrounding sinonasal tissue. This work delineates a step-by-step surgical approach to visually demonstrate the feasibility of an uninarial endoscopic endonasal approach for pediatric spontaneous CSF leak repair. A 2-year-old male with a 6-month history of clear rhinorrhea, intermittent headaches, and a previous episode of bacterial meningitis was evaluated as an inpatient consultation. Computed tomography cisternography revealed active CSF extravasation at the right sphenoid sinus roof. An endoscopic endonasal approach was performed including a complete sphenoethmoidectomy plus middle turbinectomy to provide access to the skull base defect. Once identified, a middle turbinate free mucosal graft was placed for cranial base reconstruction given the child's young agre. Sinonasal debridement 3 weeks following surgery under anesthesia revealed an intact viable graft with no evidence of CSF leak. There was no evidence of CSF leak recurrence or complications 1 year following surgery. The uninarial endoscopic endonasal approach is a safe and effective option for the surgical management of spontaneous CSF leak rhinorrhea in the pediatric population.

摘要

儿童自发性脑脊液(CSF)鼻漏是一种极其罕见的情况,当硬脑膜破裂时会发生这种情况,导致 CSF 从蛛网膜下腔排入周围的鼻窦组织。本研究详细描述了一种分步手术方法,旨在直观地展示单侧内镜经鼻入路修复儿童自发性 CSF 漏的可行性。一名 2 岁男性,有 6 个月的清亮鼻涕、间歇性头痛病史,并有一次细菌性脑膜炎发作,作为住院会诊进行评估。CT 脑池造影显示右侧蝶窦顶有活动性 CSF 外渗。进行了内镜经鼻入路手术,包括完整的蝶窦和筛窦切除术加中鼻甲切除术,以提供通往颅底缺陷的通道。由于患儿年龄较小,一旦确定,就会放置一个中鼻甲游离黏膜移植物进行颅底重建。术后 3 周在全身麻醉下进行鼻内清创术,显示移植物完整且有活性,无 CSF 漏迹象。术后 1 年无 CSF 漏复发或并发症的证据。单侧内镜经鼻入路是治疗儿童自发性 CSF 鼻漏的一种安全有效的选择。

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