Suppr超能文献

中鼻甲瓣治疗自发性瘘管的有效性

[Effectiveness of the middle turbinate flap for the treatment of spontaneous fistulas].

作者信息

Hernández-Alatriste Genaro Efraín, Torres-Zapiain Fernando, Hernández-González Martha Alicia

机构信息

Instituto Mexicano del Seguro Social, Centro Médico Nacional del Bajío, Hospital de Especialidades No. 1, Servicio de Neurocirugía. León, Guanajuato, México.

Instituto Mexicano del Seguro Social, Centro Médico Nacional del Bajío, Hospital de Especialidades No. 1, División de Investigación en Salud. León, Guanajuato, México.

出版信息

Rev Med Inst Mex Seguro Soc. 2025 May 2;63(3):e6574. doi: 10.5281/zenodo.15178461.

Abstract

BACKGROUND

Currently there is no certainty on which is the best treatment for spontaneous cerebrospinal fluid (CSF) fistulas. This study aimed to test the effectiveness of the pedicled middle turbinate flap (PMTF) in the treatment of said fistulas, located in the anterior skull base floor (ASBF).

OBJECTIVE

To demonstrate the reduction in recurrence of spontaneous CSF fistulas in the ASBF treated with endoscopic endonasal PMTF.

MATERIAL AND METHODS

Ambispective cohort study which included patients with spontaneous CSF fistulas located in the ASBF, treated with PMTF and nasoseptal flap (NSF) by endoscopic endonasal route in a third-level hospital from March 1, 2020, to February 28, 2023. 2 groups were compared: group A, for patients treated with PMTF, and group B, patients treated with NSF. It was calculated chi squared for recurrence, complications and surgical reintervention. A p value < 0.05 was considered significant.

RESULTS

The total was of 13 patients. The most frequent cause was spontaneous (9 cases). PMTF was used in 7 cases and NSF in 6. In group A the recurrence was 42%, and in group B 66% (p = 0.38). Only 1 patient in group A underwent reoperation vs. 4 in group B (p = 0.05).

CONCLUSIONS

The use of PMTF has fewer cases of recurrence compared to NSF, even though it was not statistically significant. The statistical significance for reintervention in group A suggests that PMTF may be a viable option for these patients.

摘要

背景

目前对于自发性脑脊液漏的最佳治疗方法尚无定论。本研究旨在测试带蒂中鼻甲瓣(PMTF)治疗位于前颅底(ASBF)的上述瘘管的有效性。

目的

证明经鼻内镜下带蒂中鼻甲瓣治疗ASBF自发性脑脊液漏后复发率降低。

材料与方法

回顾性队列研究,纳入2020年3月1日至2023年2月28日在一家三级医院经鼻内镜采用PMTF和鼻中隔瓣(NSF)治疗ASBF自发性脑脊液漏的患者。比较两组:A组为接受PMTF治疗的患者,B组为接受NSF治疗的患者。计算复发、并发症和再次手术干预的卡方值。p值<0.05被认为具有统计学意义。

结果

共有13例患者。最常见的病因是自发性(9例)。7例使用PMTF,6例使用NSF。A组复发率为42%,B组为66%(p = 0.38)。A组仅1例患者接受再次手术,而B组为4例(p = 0.05)。

结论

与NSF相比,使用PMTF复发病例较少,尽管无统计学意义。A组再次手术干预的统计学意义表明PMTF可能是这些患者的一个可行选择。

相似文献

1
[Effectiveness of the middle turbinate flap for the treatment of spontaneous fistulas].
Rev Med Inst Mex Seguro Soc. 2025 May 2;63(3):e6574. doi: 10.5281/zenodo.15178461.
2
Endoscopic Endonasal Reconstruction Using a Pedicled Middle Turbinate Flap for Spontaneous Cerebrospinal Fluid Rhinorrhea.
J Craniofac Surg. 2022 May 1;33(3):e318-e320. doi: 10.1097/SCS.0000000000008214. Epub 2021 Sep 30.
3
Long-term effectiveness of a reconstructive protocol using the nasoseptal flap after endoscopic skull base surgery.
World Neurosurg. 2014 Jan;81(1):136-43. doi: 10.1016/j.wneu.2012.08.011. Epub 2012 Sep 25.
5
Pedicled extranasal flaps in skull base reconstruction.
Adv Otorhinolaryngol. 2013;74:71-80. doi: 10.1159/000342282. Epub 2012 Dec 18.
6
Middle turbinate mucosal flap: Low-morbidity option in the management of skull base defects.
Head Neck. 2021 May;43(5):1415-1420. doi: 10.1002/hed.26613. Epub 2021 Jan 12.
7
Beyond the nasoseptal flap: outcomes and pearls with secondary flaps in endoscopic endonasal skull base reconstruction.
Laryngoscope. 2014 Apr;124(4):846-52. doi: 10.1002/lary.24319. Epub 2014 Jan 15.
8
Various modifications of a vascularized nasoseptal flap for repair of extensive skull base dural defects.
J Neurosurg. 2019 Feb 8;132(2):371-379. doi: 10.3171/2018.10.JNS181556. Print 2020 Feb 1.
9
Risk factors for cerebrospinal leak after endoscopic skull base reconstruction with nasoseptal flap.
Otolaryngol Head Neck Surg. 2014 Sep;151(3):516-21. doi: 10.1177/0194599814536688. Epub 2014 Jun 4.
10
Salvage endoscopic nasoseptal flap repair of persistent cerebrospinal fluid leak after open skull base surgery.
Am J Otolaryngol. 2012 Nov-Dec;33(6):735-40. doi: 10.1016/j.amjoto.2012.07.005. Epub 2012 Aug 22.

本文引用的文献

2
Pediatric Spontaneous Cerebrospinal Fluid Leak Repair: An Endoscopic Endonasal Approach.
Ear Nose Throat J. 2023 Sep;102(9_suppl):40S-42S. doi: 10.1177/01455613231184959. Epub 2023 Jul 3.
3
Endoscopic Endonasal Reconstruction Using a Pedicled Middle Turbinate Flap for Spontaneous Cerebrospinal Fluid Rhinorrhea.
J Craniofac Surg. 2022 May 1;33(3):e318-e320. doi: 10.1097/SCS.0000000000008214. Epub 2021 Sep 30.
4
Thinning of the Skull Base and Calvarial Thickness in Patients With Idiopathic Intracranial Hypertension.
J Neuroophthalmol. 2022 Jun 1;42(2):192-198. doi: 10.1097/WNO.0000000000001504. Epub 2022 Feb 15.
5
Diagnosis and Localization of Cerebrospinal Fluid Rhinorrhea: A Systematic Review.
Am J Rhinol Allergy. 2022 May;36(3):397-406. doi: 10.1177/19458924211060918. Epub 2021 Nov 30.
7
The Effectiveness and Safety of Intrathecal Fluorescein in the Management of Cerebrospinal Fluid Leaks.
Am J Rhinol Allergy. 2021 Nov;35(6):879-884. doi: 10.1177/19458924211020564. Epub 2021 Jun 1.
8
Management of cerebrospinal fluid leak: the importance of multidisciplinary approach.
Acta Otorhinolaryngol Ital. 2021 Apr;41(Suppl. 1):S18-S29. doi: 10.14639/0392-100X-suppl.1-41-2021-02.
9
Preservation of nasal turbinates in endoscopic, anterior skull base surgery-yes, we can!
Eur Arch Otorhinolaryngol. 2022 Feb;279(2):785-791. doi: 10.1007/s00405-021-06856-9. Epub 2021 May 8.
10
The Endonasal Endoscopic Management of Cerebrospinal Fluid Rhinorrhea.
Cureus. 2021 Feb 20;13(2):e13457. doi: 10.7759/cureus.13457.

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验