Hernández-Alatriste Genaro Efraín, Torres-Zapiain Fernando, Hernández-González Martha Alicia
Instituto Mexicano del Seguro Social, Centro Médico Nacional del Bajío, Hospital de Especialidades No. 1, Servicio de Neurocirugía. León, Guanajuato, México.
Instituto Mexicano del Seguro Social, Centro Médico Nacional del Bajío, Hospital de Especialidades No. 1, División de Investigación en Salud. León, Guanajuato, México.
Rev Med Inst Mex Seguro Soc. 2025 May 2;63(3):e6574. doi: 10.5281/zenodo.15178461.
Currently there is no certainty on which is the best treatment for spontaneous cerebrospinal fluid (CSF) fistulas. This study aimed to test the effectiveness of the pedicled middle turbinate flap (PMTF) in the treatment of said fistulas, located in the anterior skull base floor (ASBF).
To demonstrate the reduction in recurrence of spontaneous CSF fistulas in the ASBF treated with endoscopic endonasal PMTF.
Ambispective cohort study which included patients with spontaneous CSF fistulas located in the ASBF, treated with PMTF and nasoseptal flap (NSF) by endoscopic endonasal route in a third-level hospital from March 1, 2020, to February 28, 2023. 2 groups were compared: group A, for patients treated with PMTF, and group B, patients treated with NSF. It was calculated chi squared for recurrence, complications and surgical reintervention. A p value < 0.05 was considered significant.
The total was of 13 patients. The most frequent cause was spontaneous (9 cases). PMTF was used in 7 cases and NSF in 6. In group A the recurrence was 42%, and in group B 66% (p = 0.38). Only 1 patient in group A underwent reoperation vs. 4 in group B (p = 0.05).
The use of PMTF has fewer cases of recurrence compared to NSF, even though it was not statistically significant. The statistical significance for reintervention in group A suggests that PMTF may be a viable option for these patients.
目前对于自发性脑脊液漏的最佳治疗方法尚无定论。本研究旨在测试带蒂中鼻甲瓣(PMTF)治疗位于前颅底(ASBF)的上述瘘管的有效性。
证明经鼻内镜下带蒂中鼻甲瓣治疗ASBF自发性脑脊液漏后复发率降低。
回顾性队列研究,纳入2020年3月1日至2023年2月28日在一家三级医院经鼻内镜采用PMTF和鼻中隔瓣(NSF)治疗ASBF自发性脑脊液漏的患者。比较两组:A组为接受PMTF治疗的患者,B组为接受NSF治疗的患者。计算复发、并发症和再次手术干预的卡方值。p值<0.05被认为具有统计学意义。
共有13例患者。最常见的病因是自发性(9例)。7例使用PMTF,6例使用NSF。A组复发率为42%,B组为66%(p = 0.38)。A组仅1例患者接受再次手术,而B组为4例(p = 0.05)。
与NSF相比,使用PMTF复发病例较少,尽管无统计学意义。A组再次手术干预的统计学意义表明PMTF可能是这些患者的一个可行选择。