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弹性假黄瘤与冠状动脉疾病的详细分析

Pseudoxanthoma Elasticum With Detailed Analyses of Coronary Artery Disease.

作者信息

Fujisaki Tomohiro, Ishii Masanobu, Atari Bengo, Matsumura Tomoyo, Tsujita Kenichi

机构信息

Department of Cardiovascular Medicine, Graduate School of Medical Sciences, Kumamoto University, Kumamoto, Japan.

Department of Cardiovascular Medicine, National Cerebral and Cardiovascular Center, Osaka, Japan.

出版信息

JACC Case Rep. 2023 May 18;16:101894. doi: 10.1016/j.jaccas.2023.101894. eCollection 2023 Jun 21.

DOI:10.1016/j.jaccas.2023.101894
PMID:37396331
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10313479/
Abstract

A 60-year-old woman with pseudoxanthoma elasticum (PXE) underwent thorough coronary artery disease assessments. Intravascular imaging tests suggested fragmented and calcified elastic fibers in the internal elastic lamina, suggesting a possible pathophysiology of coronary artery disease in PXE. Our case report would allow clinicians to acknowledge the clinical picture of PXE. ().

摘要

一名患有弹性假黄瘤（PXE）的60岁女性接受了全面的冠状动脉疾病评估。血管内成像测试显示内弹力层中有破碎和钙化的弹性纤维，提示PXE中冠状动脉疾病可能的病理生理学机制。我们的病例报告将使临床医生了解PXE的临床表现。（）

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/db00/10313479/c18d3506601c/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/db00/10313479/1570dbda1a66/fx1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/db00/10313479/2a3f00a29a0a/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/db00/10313479/c18d3506601c/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/db00/10313479/1570dbda1a66/fx1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/db00/10313479/2a3f00a29a0a/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/db00/10313479/c18d3506601c/gr2.jpg

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引用本文的文献

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A male patient with pseudoxanthoma elasticum caused by isodisomy of chromosome 16 containing a nonsense variant of the gene: A quarter-century treatment experience.一名由16号染色体等二体性导致弹性假黄瘤的男性患者，该染色体包含该基因的一个无义变异：二十五年治疗经验。
Atheroscler Plus. 2025 Mar 21;60:1-5. doi: 10.1016/j.athplu.2025.03.001. eCollection 2025 Jun.
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A Case of Pseudoxanthoma Elasticum with Juvenile-onset Hypertension.一例伴青少年起病型高血压的弹性假黄瘤病例。
Intern Med. 2024 Nov 15;63(22):3121-3122. doi: 10.2169/internalmedicine.3050-23. Epub 2024 Apr 9.

本文引用的文献

1
Successful revascularization of advanced coronary artery disease associated with pseudoxanthoma elasticum.与弹性假黄瘤相关的晚期冠状动脉疾病成功血运重建。
J Cardiol Cases. 2017 Jul 27;16(4):101-104. doi: 10.1016/j.jccase.2017.05.001. eCollection 2017 Oct.
2
Etidronate for Prevention of Ectopic Mineralization in Patients With Pseudoxanthoma Elasticum.依替膦酸二钠预防弹性假黄瘤患者异位矿化。
J Am Coll Cardiol. 2018 Mar 13;71(10):1117-1126. doi: 10.1016/j.jacc.2017.12.062.
3
Proposal for updating the pseudoxanthoma elasticum classification system and a review of the clinical findings.
更新假性黄色瘤弹性组织营养不良分类系统的建议及临床发现综述。
Am J Med Genet A. 2010 Apr;152A(4):1049-58. doi: 10.1002/ajmg.a.33329.
4
Arterial conduits should be evaluated preoperatively in coronary artery bypass patients with pseudoxanthoma elasticum.对于患有弹性假黄瘤的冠状动脉搭桥手术患者，术前应评估动脉导管。
Tex Heart Inst J. 2005;32(4):576-8; discussion 578.
5
Brief report: occult pseudoxanthoma elasticum in patients with premature cardiovascular disease.简短报告：早发性心血管疾病患者中的隐匿性弹性假黄瘤
N Engl J Med. 1993 Oct 21;329(17):1237-9. doi: 10.1056/NEJM199310213291705.