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甲氨蝶呤治疗胎盘植入

Medical treatment of placenta accreta with methotrexate.

作者信息

Arulkumaran S, Ng C S, Ingemarsson I, Ratnam S S

出版信息

Acta Obstet Gynecol Scand. 1986;65(3):285-6. doi: 10.3109/00016348609155187.

DOI:10.3109/00016348609155187
PMID:3739639
Abstract

Placenta accreta is a rare condition and is associated with considerable maternal morbidity and mortality. Though the surgical approach of hysterectomy is a definitive therapy, there are occasions when conservation of the uterus is desired by the patient. We report a case of placenta accreta successfully treated with intravenous methotrexate. After 2 weeks of treatment no signs of placenta could be visualized on ultrasound examination of the uterus. The patient was discharged after 15 days and has since been well. Such therapy may be useful in exceptional cases in institutions with adequate facilities for careful monitoring and management of the patient.

摘要

胎盘植入是一种罕见的病症,与产妇的高发病率和死亡率相关。尽管子宫切除术的手术方法是一种确定性治疗,但在某些情况下患者希望保留子宫。我们报告一例经静脉注射甲氨蝶呤成功治疗的胎盘植入病例。治疗2周后,子宫超声检查未发现胎盘迹象。患者15天后出院,此后情况良好。在具备对患者进行仔细监测和管理的适当设施的机构中,这种治疗方法在特殊情况下可能会有用。

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Medical treatment of placenta accreta with methotrexate.甲氨蝶呤治疗胎盘植入
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2
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Methotrexate management for placenta accreta: a prospective study.甲氨蝶呤治疗胎盘植入:一项前瞻性研究。
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Failure of methotrexate treatment for term placenta percreta.甲氨蝶呤治疗足月穿透性胎盘失败。
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[Case report: seventeen year old primipara with placenta increta, treated with methotrexate].[病例报告:17岁初产妇合并胎盘植入,采用甲氨蝶呤治疗]
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Committee opinion no. 529: placenta accreta.委员会意见第 529 号:胎盘植入。
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High-Dose Methotrexate Treatment in a Breastfeeding Mother with Placenta Accreta: A Case Report.一名患有胎盘植入的哺乳期母亲的大剂量甲氨蝶呤治疗:病例报告
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Conservative management of placenta accreta and unruptured interstitial cornual pregnancy using methotrexate.使用甲氨蝶呤对胎盘植入和未破裂的间质部宫角妊娠进行保守治疗。
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Ethiop J Health Sci. 2020 Mar;30(2):277-292. doi: 10.4314/ejhs.v30i2.16.
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Postpartum Treatment of a Herniation of the Anterior Uterine Wall due to Remains of Placenta Increta.胎盘植入残留所致子宫前壁疝的产后治疗
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Conservative Management of Abnormally Invasive Placenta Previa after Midtrimester Foetal Demise.
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Management of placenta percreta in a Jehovah's Witness patient.耶和华见证会患者胎盘植入的管理
BMJ Case Rep. 2018 Jun 11;2018:bcr-2018-225260. doi: 10.1136/bcr-2018-225260.
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Residual adherent placenta with bladder injury: can we use methotrexate?伴有膀胱损伤的胎盘粘连残留:我们可以使用甲氨蝶呤吗?
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