Department of Dermatology, Warren Alpert Medical School of Brown University, Providence, RI, USA.
Department of Epidemiology, Richard M. Fairbanks School of Public Health, Indiana University, Indianapolis, IN, USA.
Yale J Biol Med. 2023 Jun 30;96(2):205-210. doi: 10.59249/EVKO3455. eCollection 2023 Jun.
Climate change and environmental health are closely linked with agriculture and food supply. The environment influences accessibility, quality, and variety of foods and drinks that are available for consumption, which in turn influences population health. A growing area of research is the role of dietary intake of nutrients and how they may influence risk for skin cancer. In recent years, our group has studied dietary nutrients, particularly those found in commonly consumed beverages, such as those containing caffeine, citrus products, and alcohol, in large prospective cohorts to evaluate how their intake may influence risk for skin cancer. Our data suggest that intake of citrus juices, when consumed around once per day or more, or around 5 to 6 times per week, may be associated with increased risk for both keratinocyte carcinomas (KC) and malignant melanoma (MM). With regards to alcohol consumption, we have found that intake of white wine may be associated with increased risk for both KC and MM, while beer and red wine have not shown such associations. Lastly, our work suggests caffeinated beverages, including coffee, tea, and cola, may be associated with decreased risk for basal cell carcinoma (BCC) and MM. While the associations between food intake and skin cancer development are complex, and remain to be further analyzed in future studies, we hope that our summary may help guide individuals to small changes they may make towards potentially reducing their risk for certain skin cancers.
气候变化和环境健康与农业和粮食供应密切相关。环境会影响人们可获得的食物和饮料的可及性、质量和种类，而这反过来又会影响人口健康。一个日益受到关注的研究领域是饮食中营养素的摄入及其如何影响皮肤癌风险。近年来，我们小组研究了饮食营养素，特别是那些在常见饮料中发现的营养素，如含有咖啡因、柑橘类产品和酒精的饮料，以评估其摄入量如何影响皮肤癌的风险。我们的数据表明，每天饮用一次或更多次柑橘汁，或每周饮用 5 到 6 次，可能与角质形成细胞癌 (KC) 和恶性黑素瘤 (MM) 的风险增加有关。关于酒精摄入，我们发现白葡萄酒的摄入可能与 KC 和 MM 的风险增加有关，而啤酒和红葡萄酒则没有显示出这种关联。最后，我们的工作表明，含咖啡因的饮料，包括咖啡、茶和可乐，可能与基底细胞癌 (BCC) 和 MM 的风险降低有关。尽管食物摄入与皮肤癌发展之间的关联很复杂，仍需在未来的研究中进一步分析，但我们希望我们的总结可以帮助指导个人做出一些小的改变，以潜在降低某些皮肤癌的风险。
