Bekelman Traci A, Trasande Leonardo, Law Andrew, Blackwell Courtney K, Jacobson Lisa P, Bastain Theresa M, Breton Carrie V, Elliott Amy J, Ferrara Assiamira, Karagas Margaret R, Aschner Judy L, Bornkamp Nicole, Camargo Carlos A, Comstock Sarah S, Dunlop Anne L, Ganiban Jody M, Gern James E, Karr Catherine J, Kelly Rachel S, Lyall Kristen, O'Shea T Michael, Schweitzer Julie B, LeWinn Kaja Z
Lifecourse Epidemiology of Adiposity and Diabetes (LEAD) Center, University of Colorado Anschutz Medical Campus, Aurora, CO, United States.
Department of Pediatrics, Department of Environmental Medicine, New York University Grossman School of Medicine, New York, NY, United States.
Front Pediatr. 2023 Jun 15;11:1171214. doi: 10.3389/fped.2023.1171214. eCollection 2023.
Ongoing pediatric cohort studies offer opportunities to investigate the impact of the COVID-19 pandemic on children's health. With well-characterized data from tens of thousands of US children, the Environmental influences on Child Health Outcomes (ECHO) Program offers such an opportunity.
ECHO enrolled children and their caregivers from community- and clinic-based pediatric cohort studies. Extant data from each of the cohorts were pooled and harmonized. In 2019, cohorts began collecting data under a common protocol, and data collection is ongoing with a focus on early life environmental exposures and five child health domains: birth outcomes, neurodevelopment, obesity, respiratory, and positive health. In April of 2020, ECHO began collecting a questionnaire designed to assess COVID-19 infection and the pandemic's impact on families. We describe and summarize the characteristics of children who participated in the ECHO Program during the COVID-19 pandemic and novel opportunities for scientific advancement.
This sample (= 13,725) was diverse by child age (31% early childhood, 41% middle childhood, and 16% adolescence up to age 21), sex (49% female), race (64% White, 15% Black, 3% Asian, 2% American Indian or Alaska Native, <1% Native Hawaiian or Pacific Islander, 10% Multiple race and 2% Other race), Hispanic ethnicity (22% Hispanic), and were similarly distributed across the four United States Census regions and Puerto Rico.
ECHO data collected during the pandemic can be used to conduct solution-oriented research to inform the development of programs and policies to support child health during the pandemic and in the post-pandemic era.
正在进行的儿科队列研究为调查新冠疫情对儿童健康的影响提供了机会。借助来自数万名美国儿童的详细数据，儿童健康结果的环境影响（ECHO）项目提供了这样一个契机。
ECHO从基于社区和诊所的儿科队列研究中招募儿童及其照料者。将每个队列的现有数据汇总并统一。2019年，各队列开始按照共同方案收集数据，目前数据收集仍在进行，重点是早期生活环境暴露以及五个儿童健康领域：出生结局、神经发育、肥胖、呼吸和积极健康。2020年4月，ECHO开始收集一份旨在评估新冠病毒感染及疫情对家庭影响的问卷。我们描述并总结了在新冠疫情期间参与ECHO项目的儿童的特征以及科学进步的新机遇。
该样本（=13725）在儿童年龄（31%为幼儿期，41%为童年中期，16%为18至21岁的青少年）、性别（49%为女性）、种族（64%为白人，15%为黑人，3%为亚洲人，2%为美洲印第安人或阿拉斯加原住民，<1%为夏威夷原住民或太平洋岛民，10%为多种族，2%为其他种族）、西班牙裔（22%为西班牙裔）方面具有多样性，并且在美国人口普查的四个地区和波多黎各分布相似。
疫情期间收集的ECHO数据可用于开展以解决方案为导向的研究，为制定在疫情期间及疫情后支持儿童健康的项目和政策提供参考。
