Reinhold Lauren, Lynch Stephen, Lauter Carl B, Dixon Simon R, Aneese Andrew
William Beaumont University Hospital, Royal Oak, MI, USA.
Oakland University William Beaumont School of Medicine, Rochester, MI, USA.
Case Reports Immunol. 2023 Jun 23;2023:5987123. doi: 10.1155/2023/5987123. eCollection 2023.
Kounis syndrome encompasses a variety of cardiovascular signs and symptoms associated with mast cell activation in the setting of allergic or hypersensitivity and anaphylactic or anaphylactoid insults. It can manifest as coronary vasospasm, coronary, or in-stent thrombosis, and acute myocardial infarction with plaque rupture. Various medications as well as foods including fish, shellfish, mushroom, kiwi, and rice pudding have been implicated as causal agents. We present what we believe to be the first documented case of Kounis syndrome manifesting as coronary vasospasm as the result of an allergy to banana. This case highlights the importance of considering allergic causes of angina and allergy referral in a patient with known atopy and an otherwise negative cardiovascular workup. It also emphasizes to consider food allergy, especially banana, as a cause of Kounis syndrome.
库尼斯综合征包括在过敏或超敏反应以及过敏性或类过敏性损伤情况下与肥大细胞活化相关的多种心血管体征和症状。它可表现为冠状动脉痉挛、冠状动脉或支架内血栓形成，以及伴有斑块破裂的急性心肌梗死。包括鱼、贝类、蘑菇、猕猴桃和米布丁在内的各种药物以及食物都被认为是致病因素。我们报告了我们认为是首例因对香蕉过敏而表现为冠状动脉痉挛的库尼斯综合征病例。该病例凸显了在已知特应性且心血管检查结果为阴性的患者中，考虑心绞痛的过敏原因及进行过敏转诊的重要性。它还强调要将食物过敏，尤其是香蕉过敏，视为库尼斯综合征的一个病因。
