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游离组织移植覆盖糖尿病足溃疡合并严重肢体缺血患者的动脉化静脉旁路移植物受区血管。

Arterialized Vein Bypass Graft Recipient Vessel in Free Tissue Transfer Covering Diabetic Foot Ulcers Complicated by Critical Limb Ischemia.

机构信息

From the Georgetown University School of Medicine, Washington, DC.

Department of Plastic and Reconstructive Surgery, MedStar Georgetown University Hospital, Washington, DC.

出版信息

Ann Plast Surg. 2023 Jun 1;90(6S Suppl 5):S570-S573. doi: 10.1097/SAP.0000000000003406. Epub 2023 Feb 18.

Abstract

Limb salvage options are limited in diabetic patients with critical limb ischemia. Soft tissue coverage remains technically demanding with limited recipient vessels for free tissue transfer. These factors make revascularization alone challenging. When open bypass revascularization is possible, venous bypass graft is optimal and functions as a recipient vessel for staged free tissue transfer.The authors present 2 cases using a combination approach of staged venous bypass graft revascularization followed by free tissue transfer with anastomosis to the venous bypass graft resulting in successful limb preservation.Free tissue transfer to a native vessel has limited application in severe peripheral vascular disease patients because early vascular compromise threatens flap survival. In both presented cases, venous bypass graft alone was insufficient to treat their nonhealing wounds, and preoperative angiogram revealed dismal options for free tissue transfer reconstruction. However, previous venous bypass graft provided an operable vessel for free tissue transfer anastomosis. The combination of venous bypass graft and free tissue transfer proved to be ideal for successful limb preservation by providing vascularized tissue to previously ischemic angiosomes, ensuring optimal wound healing capacity. Venous bypass graft is advantageous to native arterial grafts, and its combination with free tissue transfer likely increases graft patency and flap survival. We demonstrate that end-to-side anastomosis to a venous bypass graft is a viable option in these highly comorbid patients with favorable flap outcomes.

摘要

对于患有严重肢体缺血的糖尿病患者,肢体保留选择有限。游离组织移植的受区血管有限,软组织覆盖仍然具有技术挑战性。这些因素使得单纯血管重建具有挑战性。当可以进行开放旁路血运重建时,静脉旁路移植物是最佳选择,并且可以作为分期游离组织移植的受区血管。作者介绍了 2 例病例,采用分期静脉旁路移植血管重建联合游离组织移植的联合方法,将吻合口与静脉旁路移植吻合,成功保留了肢体。在严重外周血管疾病患者中,游离组织移植到自体血管的应用有限,因为早期血管损伤会威胁皮瓣的存活。在这两个病例中,单独的静脉旁路移植不足以治疗他们的不愈合伤口,术前血管造影显示游离组织移植重建的选择令人沮丧。然而,先前的静脉旁路移植为游离组织移植吻合提供了可操作的血管。静脉旁路移植和游离组织移植的联合应用为以前缺血的血管单元提供了有活力的组织,确保了最佳的伤口愈合能力,从而被证明是成功保留肢体的理想选择。静脉旁路移植优于自体动脉移植物,其与游离组织移植的联合应用可能会增加移植物通畅率和皮瓣存活率。我们证明,在这些合并症极高的患者中,端侧吻合至静脉旁路移植是一种可行的选择,具有良好的皮瓣效果。

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