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营养素在调节 COVID-19 疾病中的微生物组和免疫中的作用。

Role of nutrients in modulating microbiota and immunity in COVID-19 disease.

机构信息

Department of Biomedicine and Prevention, Section of Clinical Nutrition and Nutrigenomic, University of Tor Vergata, Rome, Italy.

出版信息

Eur Rev Med Pharmacol Sci. 2023 Jun;27(12):5927-5945. doi: 10.26355/eurrev_202306_32832.

DOI:10.26355/eurrev_202306_32832
PMID:37401330
Abstract

COVID-19 is a novel disease with a broad range of clinical patterns. Several patients show dysbiosis in the intestinal tract, with evidence of reduced beneficial bacteria, such as Bifidobacteria and Lactobacilli. It is well established that human gut microbiota dysbiosis is associated with several clinical conditions, including respiratory tract diseases due to the gut-lung axis. This narrative review discusses the role of nutrients in the relationship between the gut microbiota and the immune response in SARS-CoV-2 infection. In particular, we will focus on the benefits offered by vitamins and micronutrients on different aspects of COVID-19 disease while also discussing which diets seem to provide the most advantages.

摘要

新型冠状病毒肺炎(COVID-19)是一种具有广泛临床表现的新型疾病。一些患者表现出肠道内的微生态失调,有益菌如双歧杆菌和乳酸杆菌减少。已有充分证据表明,人类肠道微生物群的失调与多种临床情况有关,包括由于肠-肺轴导致的呼吸道疾病。本综述性讨论探讨了营养物质在肠道微生物群与 SARS-CoV-2 感染中的免疫反应之间的关系中的作用。特别是,我们将重点关注维生素和微量营养素在 COVID-19 疾病不同方面带来的益处,同时还讨论哪些饮食似乎提供了最大的优势。

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