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宫颈癌和子宫内膜癌的主动脉旁淋巴结活检:它会影响生存率吗?

Para-aortic node biopsy in cervical and endometrial cancers: does it affect survival?

作者信息

Blythe J G, Hodel K A, Wahl T P, Baglan R J, Lee F A, Zivnuska F R

出版信息

Am J Obstet Gynecol. 1986 Aug;155(2):306-14. doi: 10.1016/0002-9378(86)90815-x.

DOI:10.1016/0002-9378(86)90815-x
PMID:3740147
Abstract

Two hundred ten patients with endometrial and cervical carcinoma had para-aortic node biopsies. Nineteen of the 210 patients (9.0%) had positive para-aortic nodes. These 19 patients received pelvic irradiation, and 18 patients received para-aortic irradiation. The incidence of para-aortic nodal involvement in cervical carcinoma was directly related to the stage of the disease. Eleven of the 12 patients with cervical carcinoma and positive para-aortic nodes received both pelvic and para-aortic irradiation. Three of these patients are alive without disease, resulting in a survival rate of 25%. These patients are surviving for 16, 30, and 41 months. The incidence of positive para-aortic nodes in endometrial adenocarcinoma was related to the uterine length and the histologic grade. The survival rate for patients with endometrial adenocarcinoma and positive para-aortic nodes in this study was 57.1%. Four patients have survived for 1, 30, 60, and 71 months. There were no surgical deaths or radiation therapy complications directly attributable to para-aortic biopsy or irradiation.

摘要

210例子宫内膜癌和宫颈癌患者接受了腹主动脉旁淋巴结活检。210例患者中有19例(9.0%)腹主动脉旁淋巴结阳性。这19例患者接受了盆腔放疗,18例患者接受了腹主动脉旁放疗。宫颈癌腹主动脉旁淋巴结受累的发生率与疾病分期直接相关。12例宫颈癌且腹主动脉旁淋巴结阳性的患者中有11例接受了盆腔和腹主动脉旁放疗。其中3例患者无病存活,生存率为25%。这些患者分别存活了16个月、30个月和41个月。子宫内膜腺癌腹主动脉旁淋巴结阳性的发生率与子宫长度和组织学分级有关。本研究中子宫内膜腺癌且腹主动脉旁淋巴结阳性患者的生存率为57.1%。4例患者分别存活了1个月、30个月、60个月和71个月。没有直接归因于腹主动脉旁活检或放疗的手术死亡或放疗并发症。

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Para-aortic node biopsy in cervical and endometrial cancers: does it affect survival?宫颈癌和子宫内膜癌的主动脉旁淋巴结活检:它会影响生存率吗?
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引用本文的文献

1
Treatment of node-positive endometrial cancer with complete node dissection, chemotherapy and radiation therapy.采用完全淋巴结清扫术、化疗和放射治疗对淋巴结阳性子宫内膜癌进行治疗。
Br J Cancer. 1997;75(12):1836-41. doi: 10.1038/bjc.1997.313.