Department of Plastic, Reconstructive, and Hand Surgery, Maastricht University Medical Center (MUMC+), Maastricht, Limburg, The Netherlands.
Department of Plastic & Reconstructive Surgery, Erasmus MC Cancer Institute, University Medical Center Rotterdam, Rotterdam, South Holland, The Netherlands.
Head Neck. 2023 Sep;45(9):2469-2477. doi: 10.1002/hed.27450. Epub 2023 Jul 4.
Current literature on reconstruction after head and neck cancer (HNC) focusses on short-term patient-reported outcomes (PROs), while there is a need for knowledge on long-term consequences. Embase, Medline, Web of Science, and Cochrane were searched for studies on health-related quality of life (HRQoL) after HNC reconstruction, using validated PROMs in at least 50 patients, and a follow-up of more than 1 year. Thirty studies were included, comprising 2358 patients with a follow-up between one and 10 years. The most used questionnaire was the UW-QoL v4. Reconstructive surgery was generally followed by diminished oral function, worsened by radiotherapy. Patients experienced anxiety and fear of cancer recurrence. However, there was a progressive decrease in pain over time with some flaps having more favorable HRQoL outcomes. Age and bony tumor involvement were not related to postoperative HRQoL. These results may lead to better patient counseling and expectation management of HNC patients.
目前关于头颈部癌症（HNC）重建后的文献主要关注短期患者报告结果（PROs），而对于长期后果则需要更多了解。使用至少 50 名患者的经过验证的 PROMs 和超过 1 年的随访，在 Embase、Medline、Web of Science 和 Cochrane 上搜索了关于 HNC 重建后健康相关生活质量（HRQoL）的研究。共纳入 30 项研究，包括 2358 名随访时间为 1 至 10 年的患者。最常用的问卷是 UW-QoL v4。重建手术后，口腔功能通常会下降，如果再加上放射治疗，情况会更糟。患者会感到焦虑和害怕癌症复发。然而，随着时间的推移，疼痛会逐渐减轻，有些皮瓣的 HRQoL 结果更好。年龄和骨肿瘤的累及与术后 HRQoL 无关。这些结果可能会导致更好的患者咨询和对头颈癌患者的期望管理。
