人类干细胞胚胎模型：走向符合伦理的恰当监管和政策。

Human stem cell-derived embryo models: Toward ethically appropriate regulations and policies.

机构信息

Department of Health Sciences and Technology, Institute of Translational Medicine, Health Ethics and Policy Lab, Swiss Federal Institute of Technology - ETH Zurich, Hottingerstrasse 10, Zurich 8092, Switzerland.

Berman Institute of Bioethics and School of Medicine, Johns Hopkins University, 1809 Ashland Avenue, Baltimore, MD 21205, USA.

出版信息

Cell Stem Cell. 2023 Aug 3;30(8):1008-1012. doi: 10.1016/j.stem.2023.06.007. Epub 2023 Jul 3.

DOI:10.1016/j.stem.2023.06.007

PMID:37402374

Abstract

Human pluripotent stem cells can be used to derive in vitro models recapitulating post-implantation human embryos. While useful for research purposes, such integrated embryo models raise ethical issues that need to be addressed to facilitate ethically appropriate policies and regulations that permit scientific ingenuity and medical progress.

摘要

人类多能干细胞可用于体外衍生重现植入后人类胚胎的模型。尽管这些整合胚胎模型对于研究目的是有用的，但它们引发了一些需要解决的伦理问题，以促进允许科学创新和医学进步的符合伦理的政策和法规。