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比较会阴尿道造口术与尿道扩张术在前尿道狭窄疾病中的应用。

Comparison of perineal urethrostomy versus augmentation urethroplasty in anterior urethral stricture disease.

机构信息

Department of Urology, SMS Medical College and Hospital, Jaipur, Rajasthan, India.

出版信息

Urologia. 2023 Nov;90(4):689-692. doi: 10.1177/03915603231178392. Epub 2023 Jul 4.

DOI:10.1177/03915603231178392
PMID:37403482
Abstract

PURPOSE

Perineal urethrostomy and urethroplasty are very good options for complex and long anterior urethral strictures. A perineal urethroplasty is usually a neglected option. To our knowledge, a comparative study between augmentation urethroplasty and perineal urethrostomy has been not conducted regarding subjective and patient reported outcome measures. We compared both these groups in a high volume tertiary care hospital.

MATERIALS AND METHODS

A prospective comparative study of augmentation urethroplasty and perineal urethroplasty for long anterior urethral stricture. it was defined by strictures of more than 3 cm. We compared demographic data, urinary and sexual function; and quality of life using validated PROMs (patient-reported outcome measures) between both above groups.

RESULTS

Both groups had 40 patients each. IPSS score improvement for PU and AUP were 20 and 19.6, respectively( = 0.1223); IIEF-5 score improvement for PU and AUP at baseline and after 6 months were 14.3 and 16.7, respectively( = 0.1433); QOL score improvement for PU and AUP were 3.45 and 3.05, respectively; which was statistically significant ( ⩽ 0.001).

CONCLUSIONS

Perineal urethrostomy is a good but neglected option for complex and long anterior urethral strictures and it should be considered one of the reliable treatment option for patients with long-segment urethral strictures.

摘要

目的

对于复杂且长的前尿道狭窄,会阴部尿道成形术和尿道成形术是非常好的选择。会阴部尿道成形术通常是一种被忽视的选择。据我们所知,关于主观和患者报告的结果测量,还没有对尿道扩张成形术和会阴部尿道造口术进行过比较研究。我们在一家高容量的三级护理医院对这两种方法进行了比较。

材料与方法

前瞻性比较研究了尿道扩张成形术和会阴部尿道造口术治疗长段前尿道狭窄的疗效。将狭窄长度大于 3cm 的病例定义为长段前尿道狭窄。我们比较了两组患者的人口统计学数据、尿性功能和性功能;并使用经过验证的 PROM(患者报告的结果测量)评估两组患者的生活质量。

结果

两组各有 40 例患者。PU 和 AUP 的 IPSS 评分改善分别为 20 和 19.6( = 0.1223);PU 和 AUP 的 IIEF-5 评分改善在基线和 6 个月后分别为 14.3 和 16.7( = 0.1433);PU 和 AUP 的 QOL 评分改善分别为 3.45 和 3.05,差异均有统计学意义( ⩽ 0.001)。

结论

会阴部尿道造口术是治疗复杂且长的前尿道狭窄的一种较好但被忽视的选择,对于长段尿道狭窄的患者,应将其视为一种可靠的治疗选择之一。

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