Universidade Federal de Minas Gerais, Faculdade de Medicina, Laboratório de Pesquisa em Micobactérias, Belo Horizonte, Minas Gerais, Brazil.
Universidade Federal de Ouro Preto, Faculdade de Farmácia, Ouro Preto, Minas Gerais, Brazil.
Rev Inst Med Trop Sao Paulo. 2023 Jun 30;65:e42. doi: 10.1590/S1678-9946202365042. eCollection 2023.
The incidence and clinical characteristics of NTM diseases in Brazil remain relatively unknown. The present study describes the diagnosis of NTM isolates, the clinical presentation and treatment outcomes. We analyzed NTM isolates in patients of a tertiary hospital in the Southeast region of Brazil, from January 2008 to July 2019. The ATS/IDSA criteria for diagnosis and treatment of these patients was applied. Mycobacterium kansasii were identified in 13/113 (11.5%) patients. In 59/113 (52.2%) patients who met the ATS criteria for disease, 29/59 (49.1%) received treatment, and 22/29 (75.8%) were cured. The major species identified was M. kansasii. The most frequent symptoms among the treated patients were dyspnea and cough, and the proportion of cured patients was high.
巴西的 NTM 疾病发病率和临床特征尚不清楚。本研究描述了 NTM 分离株的诊断、临床表现和治疗结果。我们分析了巴西东南部一家三级医院 2008 年 1 月至 2019 年 7 月期间的 NTM 分离株。应用了 ATS/IDSA 诊断和治疗这些患者的标准。在 113 例患者中，有 13 例（11.5%）被鉴定为堪萨斯分枝杆菌。在符合 ATS 疾病标准的 59 例患者中，有 29 例（49.1%）接受了治疗，22 例（75.8%）治愈。鉴定出的主要菌种是堪萨斯分枝杆菌。接受治疗的患者最常见的症状是呼吸困难和咳嗽，治愈患者的比例较高。
