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四极质谱仪在多患者麻醉气体监测中的应用。

Adaptation of the quadrupole mass spectrometer to multipatient anaesthesia gas monitoring.

作者信息

Salamonsen R F, Tulloh A M, Boyd T

出版信息

Anaesth Intensive Care. 1986 May;14(2):163-73. doi: 10.1177/0310057X8601400212.

Abstract

A series of modifications designed to increase the suitability of the quadrupole mass spectrometer for multipatient gas monitoring in the operating suite are presented and evaluated. The adaptations include a pressure-stabilised long capillary inlet system and computer control of the quadrupole filter together with tuning, calibration and subsequent multitheatre analysis and display of clinical information. A pilot study of three months clinical monitoring provided documentation of contributions towards the safety and effectiveness of anaesthesia. These included indication of equipment malfunction, and fluctuations in gas exchange associated with inappropriate ventilation, haemodynamic instability and variations in body temperature. Limited accuracy for carbon dioxide and a low signal-to-noise ratio together with rapid ageing of electron multipliers were identified as problems still only partially solved.

摘要

本文介绍并评估了一系列旨在提高四极质谱仪在手术室中对多患者气体监测适用性的改进措施。这些改进包括压力稳定的长毛细管进样系统、四极滤质器的计算机控制以及调谐、校准,随后进行多手术室分析和临床信息显示。一项为期三个月的临床监测试点研究记录了其对麻醉安全性和有效性的贡献。这些贡献包括设备故障指示,以及与通气不当、血流动力学不稳定和体温变化相关的气体交换波动。二氧化碳测量精度有限、信噪比低以及电子倍增器快速老化被确定为仍仅部分得到解决的问题。

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